Detalles de la búsqueda
1.
Bioequivalence of rimegepant, a small molecule CGRP receptor antagonist, administered as an oral tablet, a sublingual orally disintegrating tablet, and a supralingual orally disintegrating tablet: two phase 1 randomized studies in healthy adults.
Cephalalgia
; 44(2): 3331024231219505, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38366390
2.
A placebo-controlled, randomized, single and multiple dose study to evaluate the safety, tolerability, and pharmacokinetics of rimegepant in healthy participants.
Cephalalgia
; 43(6): 3331024231179131, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37282507
3.
Effects of rimegepant 75 mg daily on the pharmacokinetics of a combined oral contraceptive containing ethinyl estradiol and norgestimate in healthy female participants.
Headache
; 63(5): 652-662, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37140071
4.
Population Pharmacokinetics Analysis To Inform Efavirenz Dosing Recommendations in Pediatric HIV Patients Aged 3 Months to 3 Years.
Antimicrob Agents Chemother
; 60(6): 3676-86, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27067333
5.
Model-Based Phase 3 Dose Selection for HIV-1 Attachment Inhibitor Prodrug BMS-663068 in HIV-1-Infected Patients: Population Pharmacokinetics/Pharmacodynamics of the Active Moiety, BMS-626529.
Antimicrob Agents Chemother
; 60(5): 2782-9, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26902761
6.
Pharmacokinetic interactions between BMS-626529, the active moiety of the HIV-1 attachment inhibitor prodrug BMS-663068, and ritonavir or ritonavir-boosted atazanavir in healthy subjects.
Antimicrob Agents Chemother
; 59(7): 3816-22, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25870057
7.
The pharmacokinetics of peginterferon lambda-1a following single dose administration to subjects with impaired renal function.
Br J Clin Pharmacol
; 80(3): 515-24, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25807956
8.
Single- and multiple-ascending dose studies to evaluate the safety, tolerability, and pharmacokinetics of daclatasvir and asunaprevir in healthy male Japanese subjects.
Int J Clin Pharmacol Ther
; 53(4): 292-302, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25740262
9.
The Pharmacokinetics, Safety, and Tolerability of Rimegepant 75 mg Are Similar in Elderly and Nonelderly Adults: A Phase 1, Open-Label, Parallel-Group, Single-Dose Study.
Clin Pharmacol Drug Dev
; 13(1): 37-44, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37904724
10.
A Drug-Drug Interaction Study to Evaluate the Impact of Rimegepant on OCT2- and MATE1-Mediated Transport of Metformin in Healthy Participants.
Clin Pharmacol Drug Dev
; 13(5): 465-473, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38174905
11.
No clinically relevant electrocardiogram effects in a randomized TQT study of single therapeutic/supratherapeutic rimegepant doses in healthy adults.
Clin Transl Sci
; 17(3): e13727, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38440916
12.
Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects.
J Infect Dis
; 206(7): 1002-11, 2012 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22896665
13.
Pharmacokinetics and Safety of Single and Multiple Daily Dosing of 75-mg Rimegepant Orally Disintegrating Tablets in Healthy Chinese Adults: A Randomized Placebo-Controlled Trial.
Clin Pharmacol Drug Dev
; 12(6): 594-601, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36808268
14.
Rimegepant 75 mg in Subjects With Hepatic Impairment: Results of a Phase 1, Open-Label, Single-Dose, Parallel-Group Study.
Clin Pharmacol Drug Dev
; 12(8): 790-800, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37073443
15.
Pharmacokinetics and inhibitory quotient of atazanavir/ritonavir versus lopinavir/ritonavir in HIV-infected, treatment-naive patients who participated in the CASTLE Study.
J Antimicrob Chemother
; 67(2): 465-8, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22121190
16.
Human Milk and Plasma Pharmacokinetics of Single-Dose Rimegepant 75 mg in Healthy Lactating Women.
Breastfeed Med
; 17(3): 277-282, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35049333
17.
P-Glycoprotein and Breast Cancer Resistance Protein Transporter Inhibition by Cyclosporine and Quinidine on the Pharmacokinetics of Oral Rimegepant in Healthy Subjects.
Clin Pharmacol Drug Dev
; 11(7): 889-897, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35304977
18.
Model-based approach for optimization of atazanavir dose recommendations for HIV-infected pediatric patients.
Antimicrob Agents Chemother
; 55(12): 5746-52, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21930880
19.
Determination of rifabutin dosing regimen when administered in combination with ritonavir-boosted atazanavir.
J Antimicrob Chemother
; 66(9): 2075-82, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21712242
20.
Effect of ondansetron on reducing ICU mortality in patients with acute kidney injury.
Sci Rep
; 11(1): 19409, 2021 09 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34593872