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1.
Bioequivalence of rimegepant, a small molecule CGRP receptor antagonist, administered as an oral tablet, a sublingual orally disintegrating tablet, and a supralingual orally disintegrating tablet: two phase 1 randomized studies in healthy adults.
Cephalalgia
; 44(2): 3331024231219505, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38366390
2.
A placebo-controlled, randomized, single and multiple dose study to evaluate the safety, tolerability, and pharmacokinetics of rimegepant in healthy participants.
Cephalalgia
; 43(6): 3331024231179131, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37282507
3.
Effects of rimegepant 75 mg daily on the pharmacokinetics of a combined oral contraceptive containing ethinyl estradiol and norgestimate in healthy female participants.
Headache
; 63(5): 652-662, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37140071
4.
Dosing regimen optimisation for oseltamivir in immunocompromised paediatric patients with influenza: Extrapolation of efficacy.
Br J Clin Pharmacol
; 88(3): 1189-1201, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34449090
5.
Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug-disease modelling for dosing regimen optimization.
Br J Clin Pharmacol
; 87(3): 1359-1368, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32808306
6.
Prevalence and Antibiogram study of Rhodococcus equi in equines of Jammu and Kashmir, India.
J Equine Sci
; 26(1): 21-4, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25829867
7.
cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists.
Bioorg Med Chem Lett
; 24(6): 1458-61, 2014 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24582476
8.
The Pharmacokinetics, Safety, and Tolerability of Rimegepant 75 mg Are Similar in Elderly and Nonelderly Adults: A Phase 1, Open-Label, Parallel-Group, Single-Dose Study.
Clin Pharmacol Drug Dev
; 13(1): 37-44, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37904724
9.
A Drug-Drug Interaction Study to Evaluate the Impact of Rimegepant on OCT2- and MATE1-Mediated Transport of Metformin in Healthy Participants.
Clin Pharmacol Drug Dev
; 13(5): 465-473, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38174905
10.
Concentration-QTc and cardiac safety analysis of single and multiple zavegepant nasal spray doses in healthy participants to support approval.
CPT Pharmacometrics Syst Pharmacol
; 13(6): 1044-1054, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38812357
11.
No clinically relevant electrocardiogram effects in a randomized TQT study of single therapeutic/supratherapeutic rimegepant doses in healthy adults.
Clin Transl Sci
; 17(3): e13727, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38440916
12.
Rimegepant 75 mg in Subjects With Hepatic Impairment: Results of a Phase 1, Open-Label, Single-Dose, Parallel-Group Study.
Clin Pharmacol Drug Dev
; 12(8): 790-800, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37073443
13.
Human Milk and Plasma Pharmacokinetics of Single-Dose Rimegepant 75 mg in Healthy Lactating Women.
Breastfeed Med
; 17(3): 277-282, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35049333
14.
P-Glycoprotein and Breast Cancer Resistance Protein Transporter Inhibition by Cyclosporine and Quinidine on the Pharmacokinetics of Oral Rimegepant in Healthy Subjects.
Clin Pharmacol Drug Dev
; 11(7): 889-897, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35304977
15.
Mechanistic Population Pharmacokinetic Model of Oseltamivir and Oseltamivir Carboxylate Accounting for Physiological Changes to Predict Exposures in Neonates and Infants.
Clin Pharmacol Ther
; 108(1): 126-135, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31957010
16.
The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells.
Eur J Pharm Sci
; 27(5): 533-42, 2006 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16289537
17.
Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells.
J Pharmacol Exp Ther
; 314(3): 1093-100, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15901802
18.
Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.
J Pharmacol Exp Ther
; 302(2): 645-50, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12130727
19.
A novel hPepT1 stably transfected cell line: establishing a correlation between expression and function.
Mol Pharm
; 1(2): 136-44, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15832510
20.
Expression of multiple drug resistance conferring proteins in normal Chinese and Caucasian small and large intestinal tissue samples.
Mol Pharm
; 1(6): 447-54, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-16028356
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