Detalles de la búsqueda
1.
Synthesis, hepatotoxic evaluation and antipyretic activity of nitrate ester analogs of the acetaminophen derivative SCP-1.
Bioorg Med Chem Lett
; 28(23-24): 3798-3801, 2018 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30327145
2.
Transcriptomic signature, bioactivity and safety of a non-hepatotoxic analgesic generating AM404 in the midbrain PAG region.
Sci Rep
; 14(1): 11103, 2024 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38750093
3.
Elovanoids are neural resiliency epigenomic regulators targeting histone modifications, DNA methylation, tau phosphorylation, telomere integrity, senescence programming, and dendrite integrity.
Res Sq
; 2023 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37502897
4.
Elovanoid-N34 modulates TXNRD1 key in protection against oxidative stress-related diseases.
Cell Death Dis
; 14(12): 819, 2023 12 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38086796
5.
Transcriptomic signature, bioactivity and safety of a non-hepatoxic analgesic generating AM404 in the mid-brain PAG region.
Res Sq
; 2023 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37205420
6.
Metal-sulfate induced generation of ROS in human brain cells: detection using an isomeric mixture of 5- and 6-carboxy-2',7'-dichlorofluorescein diacetate (carboxy-DCFDA) as a cell permeant tracer.
Int J Mol Sci
; 13(8): 9615-9626, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22949820
7.
Elovanoids Counteract Inflammatory Signaling, Autophagy, Endoplasmic Reticulum Stress, and Senescence Gene Programming in Human Nasal Epithelial Cells Exposed to Allergens.
Pharmaceutics
; 14(1)2022 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35057008
8.
New Retinal Pigment Epithelial Cell Model to Unravel Neuroprotection Sensors of Neurodegeneration in Retinal Disease.
Front Neurosci
; 16: 926629, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35873810
9.
Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.
J Biol Chem
; 285(50): 38951-60, 2010 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-20937840
10.
Elovanoids downregulate SARS-CoV-2 cell-entry, canonical mediators and enhance protective signaling in human alveolar cells.
Sci Rep
; 11(1): 12324, 2021 06 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34112906
11.
A novel pipeline of 2-(benzenesulfonamide)-N-(4-hydroxyphenyl) acetamide analgesics that lack hepatotoxicity and retain antipyresis.
Eur J Med Chem
; 202: 112600, 2020 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32629335
12.
A Nonsteroidal Novel Formulation Targeting Inflammatory and Pruritus-Related Mediators Modulates Experimental Allergic Contact Dermatitis.
Dermatol Ther (Heidelb)
; 8(1): 111-126, 2018 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-29453524
13.
Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury.
Sci Adv
; 3(9): e1700735, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28959727
14.
Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity.
Sci Rep
; 7(1): 5279, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28706274
15.
microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration.
PLoS One
; 11(3): e0150211, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26949937
16.
Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism.
Sci Rep
; 6: 30298, 2016 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27444269
17.
Beta-Amyloid Precursor Protein (ßAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD).
Mol Neurobiol
; 52(1): 533-44, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25204496
18.
Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells.
Mol Neurobiol
; 50(1): 97-106, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24293102
19.
Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line.
J Inorg Biochem
; 128: 267-9, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23778113
20.
Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a.
Neuroreport
; 24(6): 318-23, 2013 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23462268