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1.
Design, synthesis and antibacterial evaluation of novel C-11, C-9 or C-2'-substituted 3-O-descladinosyl-3-ketoclarithromycin derivatives.
Bioorg Med Chem Lett
; 43: 128110, 2021 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33991629
2.
Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus.
Bioorg Med Chem
; 28(21): 115729, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33065440
3.
Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.
Bioorg Med Chem
; 27(14): 3179-3193, 2019 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31200986
4.
Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents.
Bioorg Med Chem Lett
; 28(5): 884-891, 2018 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29433923
5.
Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine.
Bioorg Med Chem Lett
; 28(10): 1825-1831, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29657101
6.
Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors.
Bioorg Med Chem Lett
; 27(15): 3399-3402, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28633894
7.
Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition.
Bioorg Med Chem Lett
; 27(4): 958-962, 2017 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28082038
8.
Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development.
Biochem Pharmacol
; 195: 114868, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34863978
9.
Direct, stereoselective thioglycosylation enabled by an organophotoredox radical strategy.
Chem Sci
; 11(48): 13079-13084, 2020 Oct 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34094490
10.
Antimicrobial Action and Reversal of Resistance in MRSA by Difluorobenzamide Derivatives Targeted at FtsZ.
Antibiotics (Basel)
; 9(12)2020 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33291418
11.
Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain.
Eur J Med Chem
; 180: 321-339, 2019 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31323617
12.
Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators.
Eur J Med Chem
; 159: 90-103, 2018 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30268826
13.
Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds.
Curr Pharm Des
; 23(14): 2117-2130, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-27784238
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