Búsqueda | Biblioteca Virtual en Salud

1.

Therapeutic targeting of HER2-CB₂R heteromers in HER2-positive breast cancer.

Blasco-Benito, Sandra; Moreno, Estefanía; Seijo-Vila, Marta; Tundidor, Isabel; Andradas, Clara; Caffarel, María M; Caro-Villalobos, Miriam; Urigüen, Leyre; Diez-Alarcia, Rebeca; Moreno-Bueno, Gema; Hernández, Lucía; Manso, Luis; Homar-Ruano, Patricia; McCormick, Peter J; Bibic, Lucka; Bernadó-Morales, Cristina; Arribas, Joaquín; Canals, Meritxell; Casadó, Vicent; Canela, Enric I; Guzmán, Manuel; Pérez-Gómez, Eduardo; Sánchez, Cristina.

Proc Natl Acad Sci U S A ; 116(9): 3863-3872, 2019 02 26.

Artículo en Inglés | MEDLINE | ID: mdl-30733293

2.

Design and development of stapled transmembrane peptides that disrupt the activity of G-protein-coupled receptor oligomers.

Botta, Joaquín; Bibic, Lucka; Killoran, Patrick; McCormick, Peter J; Howell, Lesley A.

J Biol Chem ; 294(45): 16587-16603, 2019 11 08.

Artículo en Inglés | MEDLINE | ID: mdl-31467080

3.

A Diverse View of Science to Catalyse Change.

Urbina-Blanco, César A; Jilani, Safia Z; Speight, Isaiah R; Bojdys, Michael J; Friscic, Tomislav; Stoddart, J Fraser; Nelson, Toby L; Mack, James; Robinson, Renã A S; Waddell, Emanuel A; Lutkenhaus, Jodie L; Godfrey, Murrell; Abboud, Martine I; Aderinto, Stephen O; Aderohunmu, Damilola; Bibic, Lucka; Borges, João; Dong, Vy M; Ferrins, Lori; Fung, Fun Man; John, Torsten; Lim, Felicia P L; Masters, Sarah L; Mambwe, Dickson; Thordarson, Pall; Titirici, Maria-Magdalena; Tormet-González, Gabriela D; Unterlass, Miriam M; Wadle, Austin; Yam, Vivian W-W; Yang, Ying-Wei.

Angew Chem Int Ed Engl ; 59(42): 18306-18310, 2020 10 12.

Artículo en Inglés | MEDLINE | ID: mdl-33448562

4.

Ginsenosides Act As Positive Modulators of P2X4 Receptors.

Dhuna, Kshitija; Felgate, Matthew; Bidula, Stefan M; Walpole, Samuel; Bibic, Lucka; Cromer, Brett A; Angulo, Jesus; Sanderson, Julie; Stebbing, Martin J; Stokes, Leanne.

Mol Pharmacol ; 95(2): 210-221, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30545933

5.

Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms.

Bibic, Lucka; Herzig, Volker; King, Glenn F; Stokes, Leanne.

J Nat Prod ; 82(9): 2559-2567, 2019 09 27.

Artículo en Inglés | MEDLINE | ID: mdl-31532206

6.

A Diverse View of Science to Catalyse Change.

Urbina-Blanco, César A; Jilani, Safia Z; Speight, Isaiah R; Bojdys, Michael J; Friscic, Tomislav; Stoddart, J Fraser; Nelson, Toby L; Mack, James; Robinson, Renã A S; Waddell, Emanuel A; Lutkenhaus, Jodie L; Godfrey, Murrell; Abboud, Martine I; Aderinto, Stephen O; Aderohunmu, Damilola; Bibic, Lucka; Borges, João; Dong, Vy M; Ferrins, Lori; Fung, Fun Man; John, Torsten; Lim, Felicia P L; Masters, Sarah L; Mambwe, Dickson; Thordarson, Pall; Titirici, Maria-Magdalena; Tormet-González, Gabriela D; Unterlass, Miriam M; Wadle, Austin; Yam, Vivian W-W; Yang, Ying-Wei.

J Am Chem Soc ; 142(34): 14393-14396, 2020 08 26.

Artículo en Inglés | MEDLINE | ID: mdl-32803980

7.

Revisiting the Idea That Amyloid-ß Peptide Acts as an Agonist for P2X7.

Bibic, Lucka; Stokes, Leanne.

Front Mol Neurosci ; 13: 166, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-33071753

8.

To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?

Stokes, Leanne; Bidula, Stefan; Bibic, Lucka; Allum, Elizabeth.

Front Pharmacol ; 11: 627, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32477120

9.

Singular Location and Signaling Profile of Adenosine A_2A-Cannabinoid CB₁ Receptor Heteromers in the Dorsal Striatum.

Moreno, Estefanía; Chiarlone, Anna; Medrano, Mireia; Puigdellívol, Mar; Bibic, Lucka; Howell, Lesley A; Resel, Eva; Puente, Nagore; Casarejos, María J; Perucho, Juan; Botta, Joaquín; Suelves, Nuria; Ciruela, Francisco; Ginés, Silvia; Galve-Roperh, Ismael; Casadó, Vicent; Grandes, Pedro; Lutz, Beat; Monory, Krisztina; Canela, Enric I; Lluís, Carmen; McCormick, Peter J; Guzmán, Manuel.

Neuropsychopharmacology ; 43(5): 964-977, 2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-28102227

10.

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.

Stokes, Leanne; Layhadi, Janice A; Bibic, Lucka; Dhuna, Kshitija; Fountain, Samuel J.

Front Pharmacol ; 8: 291, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28588493

11.

Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure.

Busnelli, Marta; Kleinau, Gunnar; Muttenthaler, Markus; Stoev, Stoytcho; Manning, Maurice; Bibic, Lucka; Howell, Lesley A; McCormick, Peter J; Di Lascio, Simona; Braida, Daniela; Sala, Mariaelvina; Rovati, G Enrico; Bellini, Tommaso; Chini, Bice.

J Med Chem ; 59(15): 7152-66, 2016 08 11.

Artículo en Inglés | MEDLINE | ID: mdl-27420737

12.

A diverse view of science to catalyse change.

Urbina-Blanco, César A; Jilani, Safia Z; Speight, Isaiah R; Bojdys, Michael J; Friscic, Tomislav; Stoddart, J Fraser; Nelson, Toby L; Mack, James; Robinson, Renã A S; Waddell, Emanuel A; Lutkenhaus, Jodie L; Godfrey, Murrell; Abboud, Martine I; Aderinto, Stephen O; Aderohunmu, Damilola; Bibic, Lucka; Borges, João; Dong, Vy M; Ferrins, Lori; Fung, Fun Man; John, Torsten; Lim, Felicia P L; Masters, Sarah L; Mambwe, Dickson; Thordarson, Pall; Titirici, Maria-Magdalena; Tormet-González, Gabriela D; Unterlass, Miriam M; Wadle, Austin; Yam, Vivian W-W; Yang, Ying-Wei.

Nat Chem ; 12(9): 773-776, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32807887

13.

Learning to lead.

Bibic, Lucka.

Science ; 361(6407): 1158, 2018 Sep 14.

Artículo en Inglés | MEDLINE | ID: mdl-30213917

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Therapeutic targeting of HER2-CB₂R heteromers in HER2-positive breast cancer.

Design and development of stapled transmembrane peptides that disrupt the activity of G-protein-coupled receptor oligomers.

A Diverse View of Science to Catalyse Change.

Ginsenosides Act As Positive Modulators of P2X4 Receptors.

Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms.

A Diverse View of Science to Catalyse Change.

Revisiting the Idea That Amyloid-ß Peptide Acts as an Agonist for P2X7.

To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?

Singular Location and Signaling Profile of Adenosine A_2A-Cannabinoid CB₁ Receptor Heteromers in the Dorsal Striatum.

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.

Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure.

A diverse view of science to catalyse change.

Learning to lead.