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1.
Is detection of disease-modifying osteoarthritis drug treatment more effective when performing cartilage morphometry without blinding to MR image acquisition order?
Osteoarthritis Cartilage
; 2024 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38844160
2.
The efficacy and safety of a fixed-dose combination of apocynin and paeonol, APPA, in symptomatic knee OA: A double-blind, randomized, placebo-controlled, clinical trial.
Osteoarthritis Cartilage
; 32(7): 952-962, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38697511
3.
Impact of monitoring approaches on data quality in clinical trials.
Br J Clin Pharmacol
; 89(6): 1756-1766, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36478289
4.
Effect of adrenaline on serum mid-regional pro-atrial natriuretic peptide and central blood volume.
Exp Physiol
; 107(9): 1037-1045, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35912634
5.
Symptomatic and structural benefit of cathepsin K inhibition by MIV-711 in a subgroup with unilateral pain: post-hoc analysis of a randomised phase 2a clinical trial.
Clin Exp Rheumatol
; 40(5): 1034-1037, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35238765
6.
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study.
Ann Rheum Dis
; 80(8): 1062-1069, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33962962
7.
Safety, tolerability and pharmacokinetic characterisation of DACRA KBP-042 in healthy male subjects.
Br J Clin Pharmacol
; 87(12): 4786-4796, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34019711
8.
A biomarker perspective on the acute effect of exercise with and without impact on joint tissue turnover: an exploratory randomized cross-over study.
Eur J Appl Physiol
; 121(10): 2799-2809, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34156534
9.
Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design.
BMC Musculoskelet Disord
; 20(1): 303, 2019 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31238943
10.
Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.
JAMA
; 322(14): 1360-1370, 2019 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31593273
11.
Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis.
BMC Musculoskelet Disord
; 19(1): 17, 2018 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-29343266
12.
Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD.
Respir Res
; 18(1): 22, 2017 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-28103932
13.
Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study.
BMC Pulm Med
; 17(1): 164, 2017 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29202744
14.
High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study.
Respir Res
; 17(1): 125, 2016 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27716343
15.
The impact of clinical trial monitoring approaches on data integrity and cost--a review of current literature.
Eur J Clin Pharmacol
; 72(4): 399-412, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26729259
16.
Impact of source data verification on data quality in clinical trials: an empirical post hoc analysis of three phase 3 randomized clinical trials.
Br J Clin Pharmacol
; 79(4): 660-8, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25327707
17.
The Impact of Weight-bearing Exercise, Non-Weight-bearing Exercise, and Cardiovascular Stress on Biochemical Markers of Cartilage Turnover in Patients With Mild to Moderate Knee Osteoarthritis: A Sequential, Cross-Over, Clinical Study.
Cartilage
; : 19476035241258170, 2024 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38853398
18.
Safety, Tolerability, and Pharmacodynamics of the ADAMTS-5 Nanobody M6495: Two Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Studies in Healthy Subjects and Patients With Osteoarthritis.
ACR Open Rheumatol
; 6(4): 205-213, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38311369
19.
Joint biomarker response to mechanical stimuli in osteoarthritis - A scoping review.
Osteoarthr Cartil Open
; 5(4): 100390, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37885822
20.
Associations between single-question Visual Analogue Scale pain score and weight-bearing and non-weight-bearing domains of Western Ontario and McMaster Universities Arthritis Index pain: data from 2 phase 3 clinical trials.
Pain Rep
; 7(5): 1017, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36203646