Detalles de la búsqueda
1.
SAR of L-ABBA analogs for GGT1 inhibitory activity and L-ABBA's effect on plasma cysteine and GSH species.
Bioorg Med Chem Lett
; 92: 129406, 2023 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37423504
2.
Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
Bioorg Chem
; 111: 104884, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33872925
3.
Identification of DNA and glutathione adducts in male Sprague-Dawley rats exposed to 1-bromopropane.
J Toxicol Environ Health A
; 82(8): 502-513, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31140386
4.
Synthesis and biological evaluation of pyridine-linked indanone derivatives: Potential agents for inflammatory bowel disease.
Bioorg Med Chem Lett
; 28(14): 2436-2441, 2018 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29910080
5.
Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents.
Bioorg Med Chem
; 26(8): 1909-1919, 2018 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29510948
6.
Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines.
Bioorg Chem
; 79: 1-18, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29715635
7.
Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study.
Bioorg Med Chem Lett
; 27(5): 1205-1209, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28159411
8.
2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent.
Bioorg Med Chem Lett
; 27(15): 3279-3283, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28633898
9.
Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines.
Bioorg Med Chem Lett
; 26(7): 1726-31, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26927425
10.
Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
Bioorg Chem
; 66: 145-59, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27174797
11.
Design and synthesis of novel 2,4-diaryl-5H-indeno[1,2-b]pyridine derivatives, and their evaluation of topoisomerase inhibitory activity and cytotoxicity.
Bioorg Med Chem
; 23(1): 160-73, 2015 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25481396
12.
Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.
Bioorg Med Chem
; 23(13): 3638-54, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25936262
13.
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
Bioorg Med Chem
; 23(13): 3499-512, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26022080
14.
Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents.
Bioorg Med Chem
; 23(19): 6454-66, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26361737
15.
Comparison of red and green light for treating non-muscle invasive bladder cancer in rats using singlet oxygen-cleavable prodrugs with PPIX-PDT.
Photochem Photobiol
; 2024 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38533776
16.
Mitochondrial targeting improves the selectivity of singlet-oxygen cleavable prodrugs in NMIBC treatment.
Photochem Photobiol
; 2024 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38433310
17.
Enhancing PDT efficacy in NMIBC: Efflux inhibitor mediated improvement of PpIX levels and efficacy of the combination of PpIX-PDT and SO-cleavable prodrugs.
Photochem Photobiol
; 2024 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38866726
18.
Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.
Eur J Med Chem
; 227: 113916, 2022 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34678573
19.
Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity.
Eur J Med Chem
; 133: 69-84, 2017 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-28384547
20.
Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease.
Eur J Med Chem
; 137: 575-597, 2017 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28646757