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1.
A Recirculatory Model for Pharmacokinetics and the Effects on Bispectral Index After Intravenous Infusion of the Sedative and Anesthetic AZD3043 in Healthy Volunteers.
Anesth Analg
; 121(4): 904-913, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26097984
2.
First Human Study of the Investigational Sedative and Anesthetic Drug AZD3043: A Dose-Escalation Trial to Assess the Safety, Pharmacokinetics, and Efficacy of a 30-Minute Infusion in Healthy Male Volunteers.
Anesth Analg
; 121(4): 885-893, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26111262
3.
A Bolus and Bolus Followed by Infusion Study of AZD3043, an Investigational Intravenous Drug for Sedation and Anesthesia: Safety and Pharmacodynamics in Healthy Male and Female Volunteers.
Anesth Analg
; 121(4): 894-903, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26097986
4.
Pharmacokinetic-pharmacodynamic analysis of drug liking blockade by buprenorphine subcutaneous depot (CAM2038) in participants with opioid use disorder.
Neuropsychopharmacology
; 49(6): 1050-1057, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38200140
5.
Population Pharmacokinetic Analysis Supports Initiation Treatment and Bridging from Sublingual Buprenorphine to Subcutaneous Administration of a Buprenorphine Depot (CAM2038) in the Treatment of Opioid Use Disorder.
Clin Pharmacokinet
; 62(10): 1427-1443, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37584841
6.
Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma.
CPT Pharmacometrics Syst Pharmacol
; 12(9): 1213-1226, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37221972
7.
Modelling of pain intensity and informative dropout in a dental pain model after naproxcinod, naproxen and placebo administration.
Br J Clin Pharmacol
; 71(6): 899-906, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21272053
8.
A two-compartment effect site model describes the bispectral index after different rates of propofol infusion.
J Pharmacokinet Pharmacodyn
; 37(3): 243-55, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20414709
9.
Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582.
J Pharm Pharmacol
; 57(12): 1539-54, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16354398
10.
Performance of nonlinear mixed effects models in the presence of informative dropout.
AAPS J
; 17(1): 245-55, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25421458
11.
In vitro-in vivo correlation in man of a topically applied local anesthetic agent using numerical convolution and deconvolution.
J Pharm Sci
; 92(2): 398-406, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12532389
12.
Experiences with an adaptive design for a dose-finding study in patients with osteoarthritis.
Contemp Clin Trials
; 37(2): 189-99, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24394343
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