Detalles de la búsqueda
1.
Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro.
Drug Metab Dispos
; 36(4): 702-14, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18216275
2.
Improved xenogenic hepatocyte implantation into nude mouse liver parenchyma with acute liver failure when followed by repeated anti-Fas antibody (Jo2) treatment.
Cell Transplant
; 17(5): 507-24, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18714670
3.
Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance.
Eur J Pharm Biopharm
; 63(3): 347-55, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16621491
4.
Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations.
J Pharm Pharmacol
; 58(5): 633-41, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16640832
5.
Impact of serum on clearance predictions obtained from suspensions and primary cultures of rat hepatocytes.
Eur J Pharm Sci
; 23(2): 189-99, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15451007
6.
Increased survival despite failure of transplanted human hepatocyte implantation into liver parenchyma of nude mice with repeated lethal Jo2-induced liver deficiency.
Cell Transplant
; 23(12): 1557-72, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-23636101
7.
Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
Toxicol In Vitro
; 24(1): 346-56, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19497360
8.
Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures.
Chem Biol Interact
; 179(2-3): 247-55, 2009 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19041297
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