Detalles de la búsqueda
1.
Quantitative Real-Time PCR Assays for the Detection of Pathogenic Leptospira Species in Urine and Blood Samples in Canine Vaccine Clinical Studies: a Rapid Alternative to Classical Culture Methods.
J Clin Microbiol
; 59(7): e0300620, 2021 06 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33853840
2.
Development of a highly sensitive PCR/DNA chip method to detect mycoplasmas in a veterinary modified live vaccine.
Biologicals
; 54: 22-27, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29753589
3.
Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602.
J Chem Inf Model
; 54(11): 3238-50, 2014 Nov 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-25317974
4.
Structure-based design of PDK1 inhibitors.
Bioorg Med Chem Lett
; 22(1): 305-7, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22119465
5.
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.
Bioorg Med Chem Lett
; 22(8): 2880-4, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22437109
6.
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDK1 inhibitors discovered by fragment-based screening.
Bioorg Med Chem Lett
; 22(12): 4023-7, 2012 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22591730
7.
Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3).
J Comput Aided Mol Des
; 26(4): 437-50, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22527961
8.
Synthesis and evaluation of alkenyl indazoles as selective Aurora kinase inhibitors.
Bioorg Med Chem Lett
; 20(8): 2443-7, 2010 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20338758
9.
First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug.
Clin Transl Sci
; 13(1): 57-66, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31343094
10.
Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.
J Med Chem
; 47(4): 978-87, 2004 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-14761199
11.
Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).
J Mol Model
; 19(1): 119-30, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22820730
12.
Fragment-based ligand design of novel potent inhibitors of tankyrases.
J Med Chem
; 56(11): 4497-508, 2013 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23672613
13.
Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer.
J Med Chem
; 55(1): 169-96, 2012 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22148278
14.
Discovery of the macrocycle 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a potent Janus kinase 2/fms-like tyrosine kinase-3 (JAK2/FLT3) inhibitor for the treatment of myelofibrosis and lymphoma.
J Med Chem
; 54(13): 4638-58, 2011 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21604762
15.
Structure-based design of Aurora A & B inhibitors.
J Comput Aided Mol Des
; 22(12): 897-906, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18574696
Resultados
1 -
15
de 15
1
Próxima >
>>