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1.
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.
Mol Cancer Ther
; 7(8): 2394-404, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18723486
2.
Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitors.
J Med Chem
; 50(22): 5253-6, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17887663
3.
Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility.
PLoS One
; 10(9): e0138616, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26398286
4.
Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer.
Mol Cancer Ther
; 13(8): 2104-15, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24928852
5.
Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line.
Front Med
; 7(4): 462-76, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23820871
6.
PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activity.
Mol Cancer Ther
; 10(11): 2189-99, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21750219
7.
ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.
J Invest Dermatol
; 129(7): 1805-15, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19242509
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