Detalles de la búsqueda
1.
Oral treatment with a Brachystemma calycinum D don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog osteoarthritis: inhibition of protease-activated receptor 2.
Ann Rheum Dis
; 69(6): 1179-84, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19546097
2.
Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis.
Rheumatology (Oxford)
; 48(12): 1482-90, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19762475
3.
Cartilage in normal and osteoarthritis conditions.
Best Pract Res Clin Rheumatol
; 22(2): 351-84, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18455690
4.
The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K.
Bone
; 34(3): 527-38, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15003800
5.
Nitric oxide (NO) and cartilage metabolism: NO effects are modulated by superoxide in response to IL-1.
Biorheology
; 39(1-2): 201-14, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12082283
6.
Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis.
Nat Med
; 20(10): 1165-73, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25216639
7.
Proteinase-activated receptor-2 gene disruption limits the effect of osteoarthritis on cartilage in mice: a novel target in joint degradation.
J Rheumatol
; 38(5): 911-20, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21285164
8.
Treatment with tiludronic acid helps reduce the development of experimental osteoarthritis lesions in dogs with anterior cruciate ligament transection followed by reconstructive surgery: a 1-year study with quantitative magnetic resonance imaging.
J Rheumatol
; 38(1): 118-28, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20952474
9.
Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13.
Arthritis Res Ther
; 11(2): R41, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19291317
10.
Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
Bone
; 44(6): 1143-50, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19264156
11.
Treatment with ephrin B2 positively impacts the abnormal metabolism of human osteoarthritic chondrocytes.
Arthritis Res Ther
; 11(4): R119, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19664212
12.
Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.
Arthritis Rheum
; 58(12): 3820-30, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19035475
13.
Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling.
Arthritis Res Ther
; 10(3): R71, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18578867
14.
The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways.
Arthritis Rheum
; 56(7): 2288-98, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17599749
15.
Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study.
Arthritis Res Ther
; 9(6): R121, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-18031579
16.
Extracellular localization of galectin-3 has a deleterious role in joint tissues.
Arthritis Res Ther
; 9(1): R20, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17326835
17.
Licofelone reduces progression of structural changes in a canine model of osteoarthritis under curative conditions: effect on protease expression and activity.
J Rheumatol
; 33(6): 1176-83, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16652435
18.
Identification in human osteoarthritic chondrocytes of proteins binding to the novel regulatory site AGRE in the human matrix metalloprotease 13 proximal promoter.
Arthritis Rheum
; 54(8): 2471-80, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16868967
19.
Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes.
Arthritis Rheum
; 52(2): 488-500, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15693013
20.
The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.
Arthritis Res Ther
; 7(5): R1091-102, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16207326