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1.
NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.
FASEB J
; 29(4): 1269-79, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25477279
2.
JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production.
Arthritis Rheum
; 64(11): 3531-42, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22899318
3.
Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides.
J Biol Chem
; 285(18): 13498-506, 2010 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-20167598
4.
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship.
Bioorg Med Chem
; 19(3): 1242-55, 2011 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21236687
5.
Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship.
Bioorg Med Chem
; 18(1): 403-14, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19914076
6.
A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal models.
J Pharmacol Exp Ther
; 329(1): 14-25, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19168710
7.
Novel tight-binding inhibitory factor-kappaB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation.
J Pharmacol Exp Ther
; 330(2): 377-88, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19478133
8.
Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals.
J Exp Med
; 215(5): 1315-1325, 2018 05 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29549113
9.
Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.
PLoS One
; 7(4): e35979, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22558291
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