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1.
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines.
Org Biomol Chem
; 22(4): 767-783, 2024 01 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38167738
2.
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.
J Enzyme Inhib Med Chem
; 38(1): 2277135, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37955306
3.
Discovery of Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant.
Molecules
; 27(19)2022 Sep 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-36234966
4.
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Eur J Med Chem
; 252: 115275, 2023 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36931117
5.
Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity.
J Med Chem
; 65(17): 11550-11573, 2022 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35939763
6.
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors.
Eur J Med Chem
; 221: 113494, 2021 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33962311
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