Detalles de la búsqueda
1.
LncRNA analysis of mAb producing CHO clones reveals marker and engineering potential.
Metab Eng
; 78: 26-40, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37196898
2.
Nanopore Cas9-targeted sequencing enables accurate and simultaneous identification of transgene integration sites, their structure and epigenetic status in recombinant Chinese hamster ovary cells.
Biotechnol Bioeng
; 120(9): 2403-2418, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36938677
3.
SLAM-seq reveals early transcriptomic response mechanisms upon glutamine deprivation in Chinese hamster ovary cells.
Biotechnol Bioeng
; 120(4): 970-986, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36575109
4.
Glycosylation site Asn168 is important for slow in vivo clearance of recombinant human diamine oxidase heparin-binding motif mutants.
Glycobiology
; 32(5): 404-413, 2022 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35088086
5.
Nafamostat is a Potent Human Diamine Oxidase Inhibitor Possibly Augmenting Hypersensitivity Reactions during Nafamostat Administration.
J Pharmacol Exp Ther
; 382(2): 113-122, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35688477
6.
Inclusion of maintenance energy improves the intracellular flux predictions of CHO.
PLoS Comput Biol
; 17(6): e1009022, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34115746
7.
Diamine oxidase knockout mice are not hypersensitive to orally or subcutaneously administered histamine.
Inflamm Res
; 71(4): 497-511, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35303133
8.
Systematic use of synthetic 5'-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.
Nucleic Acids Res
; 48(20): e119, 2020 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33051690
9.
Human diamine oxidase cellular binding and internalization in vitro and rapid clearance in vivo are not mediated by N-glycans but by heparan sulfate proteoglycan interactions.
Glycobiology
; 31(4): 444-458, 2021 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32985651
10.
Enhanced targeted DNA methylation of the CMV and endogenous promoters with dCas9-DNMT3A3L entails distinct subsequent histone modification changes in CHO cells.
Metab Eng
; 66: 268-282, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33965614
11.
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes.
Metab Eng
; 66: 114-122, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33813034
12.
What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines.
Metab Eng
; 61: 288-300, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32619503
13.
Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities.
Biotechnol Bioeng
; 117(11): 3435-3447, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32662873
14.
Simple, sensitive and specific quantification of diamine oxidase activity in complex matrices using newly discovered fluorophores derived from natural substrates.
Inflamm Res
; 69(9): 937-950, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32488317
15.
Modulation of mammalian translation by a ribosome-associated tRNA half.
RNA Biol
; 17(8): 1125-1136, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32223506
16.
Oligomannosidic glycans at Asn-110 are essential for secretion of human diamine oxidase.
J Biol Chem
; 293(3): 1070-1087, 2018 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29187599
17.
Genetic engineering approaches to improve posttranslational modification of biopharmaceuticals in different production platforms.
Biotechnol Bioeng
; 116(10): 2778-2796, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31237682
18.
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture.
Biotechnol Bioeng
; 116(3): 677-692, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30512195
19.
A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells.
Metab Eng
; 48: 72-81, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29852271
20.
ChromaWizard: An open source image analysis software for multicolor fluorescence in situ hybridization analysis.
Cytometry A
; 93(7): 749-754, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30089195