Detalles de la búsqueda
1.
5-Aryltetrazoles from Direct C-H Arylation with Aryl Bromides.
J Org Chem
; 85(8): 5718-5723, 2020 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32208719
2.
Utilizing on- and off-line monitoring tools to follow a kinetic resolution step during flow synthesis.
Magn Reson Chem
; 55(4): 348-354, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27469271
3.
Discovery of a novel Kv7 channel opener as a treatment for epilepsy.
Bioorg Med Chem Lett
; 25(21): 4941-4944, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25987375
4.
1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability.
Bioorg Med Chem Lett
; 21(10): 3095-8, 2011 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21459572
5.
Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides.
Org Lett
; 21(8): 2941-2946, 2019 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30917282
6.
Transforming Benzylic Amines into Diarylmethanes: Cross-Couplings of Benzylic Pyridinium Salts via C-N Bond Activation.
Org Lett
; 20(10): 3030-3033, 2018 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-29745674
7.
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.
J Med Chem
; 60(18): 7764-7780, 2017 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28817277
8.
Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.
J Med Chem
; 60(13): 5521-5542, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28498658
9.
The biological and biochemical effects of CP-654577, a selective erbB2 kinase inhibitor, on human breast cancer cells.
Cancer Res
; 63(15): 4450-9, 2003 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12907618
10.
Reversal of Diastereoselection in the Conjugate Addition of Cuprates to Unsaturated Lactams.
Org Lett
; 17(21): 5204-7, 2015 Nov 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26485576
11.
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.
J Med Chem
; 57(3): 861-77, 2014 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24392688
12.
Unexpected migration and oxidative cyclization of substituted 2-acetophenone triflates under basic conditions: synthetic and mechanistic insights.
J Org Chem
; 68(26): 9964-70, 2003 Dec 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-14682689
Resultados
1 -
12
de 12
1
Próxima >
>>