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1.
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2).
Biochem J
; 471(3): 391-401, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26303525
2.
Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem J
; 449(1): 161-6, 2013 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23016918
3.
Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies.
Biochem J
; 438(1): 39-51, 2011 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21635223
4.
Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion.
Am J Pathol
; 175(4): 1638-52, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19729488
5.
Nonproteolytic induction of catalytic activity into the single-chain form of urokinase-type plasminogen activator by dipeptides.
Biochemistry
; 48(40): 9606-17, 2009 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-19705874
6.
Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis.
Arthritis Rheumatol
; 69(6): 1246-1256, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28235248
7.
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.
Oncotarget
; 7(13): 16773-92, 2016 Mar 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-26934448
8.
Tissue-type plasminogen activator-binding RNA aptamers inhibiting low-density lipoprotein receptor family-mediated internalisation.
Thromb Haemost
; 114(1): 139-49, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25855589
9.
Protein-binding RNA aptamers affect molecular interactions distantly from their binding sites.
PLoS One
; 10(3): e0119207, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25793507
10.
Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy.
Protein Eng Des Sel
; 27(6): 179-90, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24769623
11.
Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism.
Mol Cancer Res
; 10(12): 1532-43, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23038812
12.
Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells.
Neoplasia
; 13(9): 806-21, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21969814
13.
Activation of the zymogen to urokinase-type plasminogen activator is associated with increased interdomain flexibility.
J Mol Biol
; 411(2): 417-29, 2011 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-21669207
14.
A novel mode of intervention with serine protease activity: targeting zymogen activation.
J Biol Chem
; 284(7): 4647-57, 2009 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-19047064
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