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1.
Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.
J Med Chem
; 65(19): 12895-12924, 2022 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36127295
2.
Pharmacokinetic-pharmacodynamic modeling of tumor growth inhibition and biomarker modulation by the novel phosphatidylinositol 3-kinase inhibitor GDC-0941.
Drug Metab Dispos
; 38(9): 1436-42, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20538720
3.
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
J Med Chem
; 63(10): 5398-5420, 2020 05 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32302140
4.
Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo.
Mol Cancer Ther
; 19(10): 1970-1980, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32788207
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