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1.
Impact of hydrolysis-mediated clearance on the pharmacokinetics of novel anaplastic lymphoma kinase inhibitors.
Drug Metab Dispos
; 41(1): 238-47, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23118327
2.
Novel cannabinoid receptor 1 inverse agonist CRB-913 enhances efficacy of tirzepatide, semaglutide, and liraglutidein the diet-induced obesity mouse model.
Obesity (Silver Spring)
; 31(11): 2676-2688, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37840407
3.
Identifying symptomatic adverse events using the patient-reported outcomes version of the common terminology criteria for adverse events in patients with non-small cell lung cancer with epidermal growth factor receptor exon 20 insertion mutations.
Cancer Med
; 12(5): 5494-5505, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36583557
4.
Single-Dose Pharmacokinetics and Tolerability of the Oral Epidermal Growth Factor Receptor Inhibitor Mobocertinib (TAK-788) in Healthy Volunteers: Low-Fat Meal Effect and Relative Bioavailability of 2 Capsule Products.
Clin Pharmacol Drug Dev
; 10(9): 1028-1043, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34118178
5.
Targeting HER2 Exon 20 Insertion-Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib.
Cancer Res
; 81(20): 5311-5324, 2021 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34380634
6.
Effects of palifermin on antitumor activity of chemotherapeutic and biological agents in human head and neck and colorectal carcinoma xenograft models.
Mol Cancer Res
; 6(8): 1337-46, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18708365
7.
Dose Optimization for Anticancer Drug Combinations: Maximizing Therapeutic Index via Clinical Exposure-Toxicity/Preclinical Exposure-Efficacy Modeling.
Clin Cancer Res
; 25(22): 6633-6643, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31320596
8.
Novel Oral mTORC1/2 Inhibitor TAK-228 Has Synergistic Antitumor Effects When Combined with Paclitaxel or PI3Kα Inhibitor TAK-117 in Preclinical Bladder Cancer Models.
Mol Cancer Res
; 17(9): 1931-1944, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31160383
9.
Specific alternative HOX11 transcripts are expressed in paediatric neural tumours and T-cell acute lymphoblastic leukaemia.
Gene
; 323: 89-99, 2003 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-14659882
10.
Cross-contamination with tamoxifen induces transgene expression in non-exposed inducible transgenic mice.
Genet Mol Res
; 3(4): 456-62, 2004 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-15688312
11.
Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors.
J Med Chem
; 55(4): 1698-705, 2012 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-22263917
12.
The discovery and optimization of a novel class of potent, selective, and orally bioavailable anaplastic lymphoma kinase (ALK) inhibitors with potential utility for the treatment of cancer.
J Med Chem
; 55(14): 6523-40, 2012 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22734674
13.
Comparison of 2 cell-based phosphoprotein assays to support screening and development of an ALK inhibitor.
J Biomol Screen
; 16(2): 164-73, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21297104
14.
NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis.
Blood
; 110(10): 3753-62, 2007 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17698635
15.
The functional mapping of long-range transcription control elements of the HOX11 proto-oncogene.
Biochem Biophys Res Commun
; 313(2): 327-35, 2004 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14684164
16.
Cross-contamination with tamoxifen induces transgene expression in non-exposed inducible transgenic mice
Genet. mol. res. (Online)
; 3(4): 456-462, 2004. tab, graf
Artículo
en Inglés
| LILACS | ID: lil-410890
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