Búsqueda | Biblioteca Virtual en Salud

1.

Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.

Pariury, Holly; Fandel, Joshua; Bachl, Stefanie; Ang, Kenny K; Markossian, Sarine; Wilson, Chris G; Braun, Benjamin S; Popescu, Bogdan; Wohlfeil, Margo; Beckman, Kyle; Xirenayi, Simayijiang; Roy, Ritu P; Olshen, Adam B; Smith, Catherine; Arkin, Michelle R; Loh, Mignon L; Diaz-Flores, Ernesto.

Haematologica ; 108(5): 1272-1283, 2023 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-36700399

2.

Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies.

Marinoff, Amanda E; Aaronson, Kathryn; Agrawal, Anurag K; Braun, Benjamin S; Golden, Carla; Huang, Benjamin J; Michlitsch, Jennifer; Southworth, Erica; Thrall, Allyson; Vo, Kieuhoa T; Stieglitz, Elliot.

Pediatr Blood Cancer ; 70(6): e30335, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37036306

3.

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.

Stieglitz, Elliot; Troup, Camille B; Gelston, Laura C; Haliburton, John; Chow, Eric D; Yu, Kristie B; Akutagawa, Jon; Taylor-Weiner, Amaro N; Liu, Y Lucy; Wang, Yong-Dong; Beckman, Kyle; Emanuel, Peter D; Braun, Benjamin S; Abate, Adam; Gerbing, Robert B; Alonzo, Todd A; Loh, Mignon L.

Blood ; 125(3): 516-24, 2015 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-25395418

4.

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment.

Tran, Thai Hoa; Nguyen, Jonathan V; Stecula, Adrian; Akutagawa, Jon; Moorman, Anthony V; Braun, Benjamin S; Sali, Andrej; Mullighan, Charles G; Shah, Neil P; Dai, Yunfeng; Devidas, Meenakshi; Roberts, Kathryn G; Smith, Catherine C; Loh, Mignon L.

Haematologica ; 106(8): 2242-2245, 2021 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-33626861

5.

Targeting oncogenic Ras signaling in hematologic malignancies.

Ward, Ashley F; Braun, Benjamin S; Shannon, Kevin M.

Blood ; 120(17): 3397-406, 2012 Oct 25.

Artículo en Inglés | MEDLINE | ID: mdl-22898602

6.

Aurora Kinase A inhibition enhances DNA damage and tumor cell death with ¹³¹I-MIBG therapy in high-risk neuroblastoma.

Kumar, Prerna; Koach, Jessica; Nekritz, Erin; Mukherjee, Sucheta; Braun, Benjamin S; DuBois, Steven G; Nasholm, Nicole; Haas-Kogan, Daphne; Matthay, Katherine K; Weiss, William A; Gustafson, Clay; Seo, Youngho.

EJNMMI Res ; 14(1): 54, 2024 Jun 13.

Artículo en Inglés | MEDLINE | ID: mdl-38869684

7.

Aurora Kinase A inhibition enhances DNA damage and tumor cell death with ¹³¹I-MIBG therapy in high-risk neuroblastoma.

Kumar, Prerna; Koach, Jessica; Nekritz, Erin; Mukherjee, Sucheta; Braun, Benjamin S; DuBois, Steven G; Nasholm, Nicole; Haas-Kogan, Daphne; Matthay, Katherine K; Weiss, William A; Gustafson, Clay; Seo, Youngho.

Res Sq ; 2024 Jan 18.

Artículo en Inglés | MEDLINE | ID: mdl-38313265

8.

Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.

Li, Qing; Haigis, Kevin M; McDaniel, Andrew; Harding-Theobald, Emily; Kogan, Scott C; Akagi, Keiko; Wong, Jasmine C Y; Braun, Benjamin S; Wolff, Linda; Jacks, Tyler; Shannon, Kevin.

Blood ; 117(6): 2022-32, 2011 Feb 10.

Artículo en Inglés | MEDLINE | ID: mdl-21163920

9.

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.

Chan, Gordon; Cheung, Laurene S; Yang, Wentian; Milyavsky, Michael; Sanders, Ashley D; Gu, Shengqing; Hong, Wan Xing; Liu, Aurora X; Wang, Xiaonan; Barbara, Mary; Sharma, Tarun; Gavin, Joehleen; Kutok, Jeffery L; Iscove, Norman N; Shannon, Kevin M; Dick, John E; Neel, Benjamin G; Braun, Benjamin S.

Blood ; 117(16): 4253-61, 2011 Apr 21.

Artículo en Inglés | MEDLINE | ID: mdl-21398220

10.

Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.

Dail, Monique; Li, Qing; McDaniel, Andrew; Wong, Jason; Akagi, Keiko; Huang, Ben; Kang, Hio Chung; Kogan, Scott C; Shokat, Kevan; Wolff, Linda; Braun, Benjamin S; Shannon, Kevin.

Proc Natl Acad Sci U S A ; 107(11): 5106-11, 2010 Mar 16.

Artículo en Inglés | MEDLINE | ID: mdl-20194733

11.

Oncogenic Kras initiates leukemia in hematopoietic stem cells.

Sabnis, Amit J; Cheung, Laurene S; Dail, Monique; Kang, Hio Chung; Santaguida, Marianne; Hermiston, Michelle L; Passegué, Emmanuelle; Shannon, Kevin; Braun, Benjamin S.

PLoS Biol ; 7(3): e59, 2009 Mar 17.

Artículo en Inglés | MEDLINE | ID: mdl-19296721

12.

The sum is greater than the FGFR1 partner.

Braun, Benjamin S; Shannon, Kevin.

Cancer Cell ; 5(3): 203-4, 2004 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-15050910

13.

Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia.

Morales, Carolina E; Stieglitz, Elliot; Kogan, Scott C; Loh, Mignon L; Braun, Benjamin S.

Blood Adv ; 5(18): 3587-3591, 2021 09 28.

Artículo en Inglés | MEDLINE | ID: mdl-34464969

14.

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.

Wong, Jasmine C; Perez-Mancera, Pedro A; Huang, Tannie Q; Kim, Jangkyung; Grego-Bessa, Joaquim; Del Pilar Alzamora, Maria; Kogan, Scott C; Sharir, Amnon; Keefe, Susan H; Morales, Carolina E; Schanze, Denny; Castel, Pau; Hirose, Kentaro; Huang, Guo N; Zenker, Martin; Sheppard, Dean; Klein, Ophir D; Tuveson, David A; Braun, Benjamin S; Shannon, Kevin.

JCI Insight ; 5(21)2020 11 05.

Artículo en Inglés | MEDLINE | ID: mdl-32990679

15.

KIT's ship comes in.

Braun, Benjamin S.

Blood ; 120(13): 2541-2, 2012 Sep 27.

Artículo en Inglés | MEDLINE | ID: mdl-23019203

16.

Targeting Ras in myeloid leukemias.

Braun, Benjamin S; Shannon, Kevin.

Clin Cancer Res ; 14(8): 2249-52, 2008 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-18413813

17.

Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.

Diaz-Flores, Ernesto; Comeaux, Evan Q; Kim, Kailyn L; Melnik, Ella; Beckman, Kyle; Davis, Kara L; Wu, Kevin; Akutagawa, Jon; Bridges, Olga; Marino, Roberta; Wohlfeil, Margo; Braun, Benjamin S; Mullighan, Charles G; Loh, Mignon L.

Cancer Res ; 79(9): 2339-2351, 2019 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-30862722

18.

Tissue-Specific Oncogenic Activity of KRAS^A146T.

Poulin, Emily J; Bera, Asim K; Lu, Jia; Lin, Yi-Jang; Strasser, Samantha Dale; Paulo, Joao A; Huang, Tannie Q; Morales, Carolina; Yan, Wei; Cook, Joshua; Nowak, Jonathan A; Brubaker, Douglas K; Joughin, Brian A; Johnson, Christian W; DeStefanis, Rebecca A; Ghazi, Phaedra C; Gondi, Sudershan; Wales, Thomas E; Iacob, Roxana E; Bogdanova, Lana; Gierut, Jessica J; Li, Yina; Engen, John R; Perez-Mancera, Pedro A; Braun, Benjamin S; Gygi, Steven P; Lauffenburger, Douglas A; Westover, Kenneth D; Haigis, Kevin M.

Cancer Discov ; 9(6): 738-755, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30952657

19.

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.

Maertens, Ophélia; McCurrach, Mila E; Braun, Benjamin S; De Raedt, Thomas; Epstein, Inbal; Huang, Tannie Q; Lauchle, Jennifer O; Lee, Hyerim; Wu, Jianqiang; Cripe, Timothy P; Clapp, D Wade; Ratner, Nancy; Shannon, Kevin; Cichowski, Karen.

Cancer Res ; 77(21): 5706-5711, 2017 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-28993414

20.

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Stieglitz, Elliot; Mazor, Tali; Olshen, Adam B; Geng, Huimin; Gelston, Laura C; Akutagawa, Jon; Lipka, Daniel B; Plass, Christoph; Flotho, Christian; Chehab, Farid F; Braun, Benjamin S; Costello, Joseph F; Loh, Mignon L.

Nat Commun ; 8(1): 2127, 2017 12 19.

Artículo en Inglés | MEDLINE | ID: mdl-29259179

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Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.

Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies.

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment.

Targeting oncogenic Ras signaling in hematologic malignancies.

Aurora Kinase A inhibition enhances DNA damage and tumor cell death with ¹³¹I-MIBG therapy in high-risk neuroblastoma.

Aurora Kinase A inhibition enhances DNA damage and tumor cell death with ¹³¹I-MIBG therapy in high-risk neuroblastoma.

Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.

Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.

Oncogenic Kras initiates leukemia in hematopoietic stem cells.

The sum is greater than the FGFR1 partner.

Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia.

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.

KIT's ship comes in.

Targeting Ras in myeloid leukemias.

Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.

Tissue-Specific Oncogenic Activity of KRAS^A146T.

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.