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1.
Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
Genes Dev
; 28(13): 1429-44, 2014 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24990963
2.
Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease.
J Pharmacol Exp Ther
; 374(2): 342-353, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32487538
3.
FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition.
Pharm Res
; 33(8): 1833-49, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27059922
4.
A procollagen C-proteinase inhibitor diminishes collagen and lysyl oxidase processing but not collagen cross-linking in osteoblastic cultures.
J Cell Physiol
; 203(1): 111-7, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15368541
5.
Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.
J Biol Chem
; 279(53): 55051-9, 2004 Dec 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-15485863
6.
Transforming growth factor-beta induces secretion of activated ADAMTS-2. A procollagen III N-proteinase.
J Biol Chem
; 278(21): 19549-57, 2003 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-12646579
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