Búsqueda | Biblioteca Virtual en Salud

1.

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.

Shih, D Q; Bussen, M; Sehayek, E; Ananthanarayanan, M; Shneider, B L; Suchy, F J; Shefer, S; Bollileni, J S; Gonzalez, F J; Breslow, J L; Stoffel, M.

Nat Genet ; 27(4): 375-82, 2001 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-11279518

2.

Mouse models of atherosclerosis.

Breslow, J L.

Science ; 272(5262): 685-8, 1996 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-8614828

3.

Heritable allele-specific differences in amounts of apoB and low-density lipoproteins in plasma.

Gavish, D; Brinton, E A; Breslow, J L.

Science ; 244(4900): 72-6, 1989 Apr 07.

Artículo en Inglés | MEDLINE | ID: mdl-2565046

4.

Enhanced dexamethasone resistance in cystic fibrosis cells: potential use for heterozygote detection and prenatal diagnosis.

Breslow, J L; Epstein, J; Fontaine, J H; Forbes, G B.

Science ; 201(4351): 180-2, 1978 Jul 14.

Artículo en Inglés | MEDLINE | ID: mdl-663650

5.

Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice.

Ito, Y; Azrolan, N; O'Connell, A; Walsh, A; Breslow, J L.

Science ; 249(4970): 790-3, 1990 Aug 17.

Artículo en Inglés | MEDLINE | ID: mdl-2167514

6.

A mouse model with features of familial combined hyperlipidemia.

Masucci-Magoulas, L; Goldberg, I J; Bisgaier, C L; Serajuddin, H; Francone, O L; Breslow, J L; Tall, A R.

Science ; 275(5298): 391-4, 1997 Jan 17.

Artículo en Inglés | MEDLINE | ID: mdl-8994037

7.

Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene.

Gavish, D; Azrolan, N; Breslow, J L.

J Clin Invest ; 84(6): 2021-7, 1989 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-2556454

8.

Increased apo A-I and apo A-II fractional catabolic rate in patients with low high density lipoprotein-cholesterol levels with or without hypertriglyceridemia.

Brinton, E A; Eisenberg, S; Breslow, J L.

J Clin Invest ; 87(2): 536-44, 1991 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-1899429

9.

Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.

Weintraub, M S; Eisenberg, S; Breslow, J L.

J Clin Invest ; 80(6): 1571-7, 1987 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-3479440

10.

Elevated high density lipoprotein cholesterol levels correlate with decreased apolipoprotein A-I and A-II fractional catabolic rate in women.

Brinton, E A; Eisenberg, S; Breslow, J L.

J Clin Invest ; 84(1): 262-9, 1989 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-2500457

11.

Polymorphism in the human apolipoprotein A-I gene promoter region. Association of the minor allele with decreased production rate in vivo and promoter activity in vitro.

Smith, J D; Brinton, E A; Breslow, J L.

J Clin Invest ; 89(6): 1796-800, 1992 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-1601989

12.

Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with cholestyramine and gemfibrozil.

Weintraub, M S; Eisenberg, S; Breslow, J L.

J Clin Invest ; 79(4): 1110-9, 1987 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-3470306

13.

A low-fat diet decreases high density lipoprotein (HDL) cholesterol levels by decreasing HDL apolipoprotein transport rates.

Brinton, E A; Eisenberg, S; Breslow, J L.

J Clin Invest ; 85(1): 144-51, 1990 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-2104877

14.

Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences.

Jiang, X C; Agellon, L B; Walsh, A; Breslow, J L; Tall, A.

J Clin Invest ; 90(4): 1290-5, 1992 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-1401066

15.

Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.

Weintraub, M S; Zechner, R; Brown, A; Eisenberg, S; Breslow, J L.

J Clin Invest ; 82(6): 1884-93, 1988 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-3058748

16.

Decreased cholesteryl ester transfer protein (CETP) mRNA and protein and increased high density lipoprotein following lipopolysaccharide administration in human CETP transgenic mice.

Masucci-Magoulas, L; Moulin, P; Jiang, X C; Richardson, H; Walsh, A; Breslow, J L; Tall, A.

J Clin Invest ; 95(4): 1587-94, 1995 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-7706465

17.

Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels.

Masucci-Magoulas, L; Plump, A; Jiang, X C; Walsh, A; Breslow, J L; Tall, A R.

J Clin Invest ; 97(1): 154-61, 1996 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-8550828

18.

Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice.

Zhong, S; Goldberg, I J; Bruce, C; Rubin, E; Breslow, J L; Tall, A.

J Clin Invest ; 94(6): 2457-67, 1994 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-7989603

19.

Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (Apo) A-I. Presentation of a new animal model and mechanistic studies in human Apo A-I transgenic and control mice.

Hayek, T; Ito, Y; Azrolan, N; Verdery, R B; Aalto-Setälä, K; Walsh, A; Breslow, J L.

J Clin Invest ; 91(4): 1665-71, 1993 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-8473509

20.

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene.

Hayek, T; Masucci-Magoulas, L; Jiang, X; Walsh, A; Rubin, E; Breslow, J L; Tall, A R.

J Clin Invest ; 96(4): 2071-4, 1995 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-7560101

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Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.

Mouse models of atherosclerosis.

Heritable allele-specific differences in amounts of apoB and low-density lipoproteins in plasma.

Enhanced dexamethasone resistance in cystic fibrosis cells: potential use for heterozygote detection and prenatal diagnosis.

Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice.

A mouse model with features of familial combined hyperlipidemia.

Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene.

Increased apo A-I and apo A-II fractional catabolic rate in patients with low high density lipoprotein-cholesterol levels with or without hypertriglyceridemia.

Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.

Elevated high density lipoprotein cholesterol levels correlate with decreased apolipoprotein A-I and A-II fractional catabolic rate in women.

Polymorphism in the human apolipoprotein A-I gene promoter region. Association of the minor allele with decreased production rate in vivo and promoter activity in vitro.

Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with cholestyramine and gemfibrozil.

A low-fat diet decreases high density lipoprotein (HDL) cholesterol levels by decreasing HDL apolipoprotein transport rates.

Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences.

Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.

Decreased cholesteryl ester transfer protein (CETP) mRNA and protein and increased high density lipoprotein following lipopolysaccharide administration in human CETP transgenic mice.

Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels.

Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice.

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene.