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1.
Convolution-based approach for modeling the paliperidone extended release and Long-Acting Injectable (LAI) PK of once-, and three-monthly products administration and for optimizing the development of new LAI products.
J Pharmacokinet Pharmacodyn
; 50(2): 89-96, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36484885
2.
Model based approach for estimating the dosage regimen of indomethacin a potential antiviral treatment of patients infected with SARS CoV-2.
J Pharmacokinet Pharmacodyn
; 47(3): 189-198, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32435882
3.
High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death.
Antimicrob Agents Chemother
; 61(8)2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28607017
4.
Artificial intelligence approach for the analysis of placebo-controlled clinical trials in major depressive disorders accounting for individual propensity to respond to placebo.
Transl Psychiatry
; 13(1): 141, 2023 04 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-37120641
5.
A new method for analyzing clinical trials in depression based on individual propensity to respond to placebo estimated using artificial intelligence.
Psychiatry Res
; 327: 115367, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37544088
6.
Interpreting clinical trial outcomes complicated by placebo response with an assessment of false-negative and true-negative clinical trials in depression using propensity-weighting.
Transl Psychiatry
; 13(1): 388, 2023 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38097546
7.
Modeling Complex Pharmacokinetics of Long-Acting Injectable Products Using Convolution-Based Models With Nonparametric Input Functions.
J Clin Pharmacol
; 61(8): 1081-1095, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33606280
8.
Comparison of Alternative Population Modeling Approaches for Implementing a Level A IVIVC and for Assessing the Time-Scaling Factor Using Deconvolution and Convolution-Based Methods.
AAPS J
; 22(3): 67, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32297044
9.
Deconvolution Analysis by Non-linear Regression Using a Convolution-Based Model: Comparison of Nonparametric and Parametric Approaches.
AAPS J
; 22(1): 9, 2019 12 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31820258
10.
Model-Informed Approach to Assess the Treatment Effect Conditional to the Level of Placebo Response.
Clin Pharmacol Ther
; 106(6): 1253-1260, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31397904
11.
A General Framework for Assessing In vitro/In vivo Correlation as a Tool for Maximizing the Benefit-Risk Ratio of a Treatment Using a Convolution-Based Modeling Approach.
CPT Pharmacometrics Syst Pharmacol
; 8(2): 97-106, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30659771
12.
Is It Time for Going Beyond the P-Value Paradigm With the Estimation of the Probability of Clinical Benefit as a Criterion for Assessing the Outcomes of a Clinical Trial? A Case Study in Patients With Major Depressive Disorder.
J Clin Pharmacol
; 58(6): 740-749, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29372561
13.
Liquid chromatography-electrospray ionization-tandem mass spectrometry method for quantitative estimation of new imiqualine leads with potent anticancer activities in rat and mouse plasma. Application to a pharmacokinetic study in mice.
J Pharm Biomed Anal
; 148: 369-379, 2018 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29111492
14.
Response Surface Analysis and Nonlinear Optimization Algorithm for Maximization of Clinical Drug Performance: Application to Extended-Release and Long-Acting Injectable Paliperidone.
J Clin Pharmacol
; 56(10): 1296-306, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26899406
15.
Development and validation of a liquid chromatography-electrospray ionization-tandem mass spectrometry method for the determination of urolithin C in rat plasma and its application to a pharmacokinetic study.
J Pharm Biomed Anal
; 131: 33-39, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521987
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