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1.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Toxicol Appl Pharmacol
; 394: 114961, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32209365
2.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Toxicol Appl Pharmacol
; 395: 114983, 2020 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32247767
3.
Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839.
J Pharmacol Exp Ther
; 350(2): 469-78, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24917547
4.
Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?
Front Physiol
; 13: 850782, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35600303
5.
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Sci Rep
; 10(1): 11884, 2020 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32665705
6.
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Sci Rep
; 10(1): 5627, 2020 03 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32221320
7.
A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm.
J Biomol Screen
; 21(1): 1-11, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26170255
8.
Evaluation of drug-induced QT interval prolongation in animal and human studies: a literature review of concordance.
Br J Pharmacol
; 172(16): 4002-11, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26031452
9.
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Toxicol Sci
; 137(1): 189-211, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24085192
10.
Prediction of Thorough QT study results using action potential simulations based on ion channel screens.
J Pharmacol Toxicol Methods
; 70(3): 246-54, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25087753
11.
Prospective Prediction of Antitarget Activity by Matched Molecular Pairs Analysis.
Mol Inform
; 31(5): 365-8, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-27477265
12.
Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in beagle dog left ventricular midmyocardial myocytes.
J Pharmacol Toxicol Methods
; 60(1): 94-106, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19414070
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