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1.
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.
Immunity
; 45(2): 389-401, 2016 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521269
2.
EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22.
PLoS Pathog
; 18(1): e1010200, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35025968
3.
Clinical and molecular effects of oral CCR4 antagonist RPT193 in atopic dermatitis: A Phase 1 study.
Allergy
; 79(4): 924-936, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-37984453
4.
A Potent and Effective Suicidal Listeria Vaccine Platform.
Infect Immun
; 87(8)2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31235641
5.
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Gastroenterology
; 146(7): 1784-94.e6, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24607504
6.
Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.
J Med Chem
; 65(19): 12895-12924, 2022 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36127295
7.
KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity.
J Clin Invest
; 118(12): 3990-4001, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19033668
8.
Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria.
PLoS Pathog
; 5(9): e1000568, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19730694
9.
Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes.
J Exp Med
; 200(4): 527-33, 2004 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-15302899
10.
Single-Cell Immune Competency Signatures Associate with Survival in Phase II GVAX and CRS-207 Randomized Studies in Patients with Metastatic Pancreatic Cancer.
Cancer Immunol Res
; 8(5): 609-617, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32132105
11.
Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4.
J Immunother Cancer
; 8(2)2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33243932
12.
Evaluation of Cyclophosphamide/GVAX Pancreas Followed by Listeria-Mesothelin (CRS-207) with or without Nivolumab in Patients with Pancreatic Cancer.
Clin Cancer Res
; 26(14): 3578-3588, 2020 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32273276
13.
Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors.
J Med Chem
; 63(15): 8584-8607, 2020 08 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32667798
14.
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
J Med Chem
; 63(10): 5398-5420, 2020 05 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32302140
15.
Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo.
Mol Cancer Ther
; 19(10): 1970-1980, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32788207
16.
Impact of preexisting vector-specific immunity on vaccine potency: characterization of listeria monocytogenes-specific humoral and cellular immunity in humans and modeling studies using recombinant vaccines in mice.
Infect Immun
; 77(9): 3958-68, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19528221
17.
Clinical Response of Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma.
Clin Cancer Res
; 25(19): 5787-5798, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31263030
18.
Results from a Phase IIb, Randomized, Multicenter Study of GVAX Pancreas and CRS-207 Compared with Chemotherapy in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma (ECLIPSE Study).
Clin Cancer Res
; 25(18): 5493-5502, 2019 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31126960
19.
Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains.
Infect Immun
; 76(8): 3742-53, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18541651
20.
Selective targeting of antitumor immune responses with engineered live-attenuated Listeria monocytogenes.
Cancer Res
; 66(2): 1096-104, 2006 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16424046