Detalles de la búsqueda
1.
Regulation of androgen receptor activity by tyrosine phosphorylation.
Cancer Cell
; 10(4): 309-19, 2006 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17045208
2.
Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells.
J Biol Chem
; 286(41): 36152-36160, 2011 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21878636
3.
Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer.
Breast Cancer Res Treat
; 124(2): 585-91, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20623181
4.
Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro.
Mol Cancer Ther
; 7(1): 121-32, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18202015
5.
Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer.
Mol Cancer Ther
; 7(8): 2348-57, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18723482
6.
Aromatase inhibitors: are there differences between steroidal and nonsteroidal aromatase inhibitors and do they matter?
Oncologist
; 13(8): 829-37, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18695261
7.
Effects of novel retinoic acid metabolism blocking agent (VN/14-1) on letrozole-insensitive breast cancer cells.
Cancer Res
; 66(23): 11485-93, 2006 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17145897
8.
Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer.
Steroids
; 72(1): 7-25, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17169390
9.
Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole.
Cancer Res
; 65(12): 5380-9, 2005 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15958587
10.
Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model.
Cancer Res
; 65(12): 5439-44, 2005 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15958593
11.
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
J Med Chem
; 48(8): 2972-84, 2005 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-15828836
12.
Effects of exemestane and tamoxifen in a postmenopausal breast cancer model.
Clin Cancer Res
; 10(21): 7375-81, 2004 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15534114
13.
Discovery and development of Galeterone (TOK-001 or VN/124-1) for the treatment of all stages of prostate cancer.
J Med Chem
; 58(5): 2077-87, 2015 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25591066
14.
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
J Med Chem
; 46(12): 2345-51, 2003 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-12773039
15.
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
J Med Chem
; 47(27): 6716-29, 2004 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-15615521
16.
Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.
J Steroid Biochem Mol Biol
; 92(3): 155-65, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15555909
17.
Pharmacokinetics of novel inhibitors of androgen synthesis after intravenous administration in mice.
Cancer Chemother Pharmacol
; 51(6): 519-24, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12715204
18.
Novel P450(17alpha) inhibitors: 17-(2'-oxazolyl)- and 17-(2'-thiazolyl)-androstene derivatives.
Steroids
; 68(7-8): 603-11, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12957665
19.
Combined cancer therapy: strategies to overcome acquired aromatase inhibitor resistance.
Curr Pharm Des
; 20(42): 6575-83, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25341934
20.
Upregulation of AIB1, aromatase and ERα provides long-term estrogen-deprived human breast cancer cells with a mechanistic growth advantage for survival.
Horm Mol Biol Clin Investig
; 3(1): 357-366, 2011 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23606920