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1.
IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau.
J Proteome Res
; 22(4): 1309-1321, 2023 04 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36888912
2.
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein.
Proc Natl Acad Sci U S A
; 107(1): 308-13, 2010 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-19966279
3.
Recombinant expression, purification and dimerization of the neurotrophic growth factor Artemin for in vitro and in vivo use.
Protein Expr Purif
; 81(1): 25-32, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21907286
4.
Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.
J Med Chem
; 65(15): 10419-10440, 2022 08 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35862732
5.
2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
J Med Chem
; 50(18): 4261-4, 2007 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-17685503
6.
Investigation of signalling cascades induced by neurotrophic synaptolepis factor K7 reveals a critical role for novel PKCε.
Eur J Pharmacol
; 701(1-3): 73-81, 2013 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23340224
7.
Exceptional stability of artemin neurotrophic factor dimers: effects of temperature, pH, buffer and storage conditions on protein integrity and activity.
Appl Biochem Biotechnol
; 165(5-6): 1379-90, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21892665
8.
Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography.
Protein Expr Purif
; 26(1): 139-48, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12356481
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