Detalles de la búsqueda
1.
Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements.
Chem Res Toxicol
; 36(2): 243-250, 2023 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36705520
2.
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s.
Arch Toxicol
; 96(11): 3077-3089, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35882637
3.
Toxicity of Ortho-phthalaldehyde Aerosols in a Human In Vitro Airway Tissue Model.
Chem Res Toxicol
; 34(3): 754-766, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33556243
4.
Effects of maternal and lactational exposure to 2-hydroxy-4-methoxybenzone on development and reproductive organs in male and female rat offspring.
Birth Defects Res B Dev Reprod Toxicol
; 104(1): 35-51, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25707689
5.
In vivo pharmacokinetic analyses of placental transfer of three drugs of different physicochemical properties in pregnant rats.
Reprod Toxicol
; 111: 194-203, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35714934
6.
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats.
Food Chem Toxicol
; 160: 112780, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34965465
7.
The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells.
Toxicol Lett
; 344: 58-68, 2021 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33727136
8.
14-Day Nose-Only Inhalation Toxicity and Haber's Rule Study of NNK in Sprague-Dawley Rats.
Toxicol Sci
; 183(2): 319-337, 2021 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34329464
9.
Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage.
Toxicol Sci
; 182(1): 10-28, 2021 07 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33944952
10.
Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.
Food Chem Toxicol
; 145: 111662, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32798647
11.
From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats.
Toxicol Sci
; 158(2): 302-318, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28525602
12.
The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
Toxicol Lett
; 253: 55-62, 2016 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-27113703
13.
Differential Effects of Silver Nanoparticles and Silver Ions on Tissue Accumulation, Distribution, and Toxicity in the Sprague Dawley Rat Following Daily Oral Gavage Administration for 13 Weeks.
Toxicol Sci
; 150(1): 131-60, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26732888
14.
Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents.
Food Chem Toxicol
; 94: 39-56, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27234134
15.
A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer.
J Mass Spectrom
; 40(10): 1347-56, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16206149
16.
Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 767(2): 353-62, 2002 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-11885864
17.
Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism.
J Nutr Biochem
; 25(12): 1235-42, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25256357
18.
Toxicity evaluation of bisphenol A administered by gavage to Sprague Dawley rats from gestation day 6 through postnatal day 90.
Toxicol Sci
; 139(1): 174-97, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24496637
19.
Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90.
Toxicol Sci
; 153(1): 212, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27506224
20.
Simultaneously quantifying parent drugs and screening for metabolites in plasma pharmacokinetic samples using selected reaction monitoring information-dependent acquisition on a QTrap instrument.
Rapid Commun Mass Spectrom
; 19(14): 1943-50, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15954168