Detalles de la búsqueda
1.
Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives.
Bioorg Med Chem
; 28(8): 115431, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32197813
2.
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety.
Bioorg Med Chem
; 28(11): 115497, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32312487
3.
Graphene Quantum Dots Based Systems As HIV Inhibitors.
Bioconjug Chem
; 29(9): 3084-3093, 2018 09 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30106563
4.
Identification of influenza PA-Nter endonuclease inhibitors using pharmacophore- and docking-based virtual screening.
Bioorg Med Chem
; 26(15): 4544-4550, 2018 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30082105
5.
Structural optimization of N1-aryl-benzimidazoles for the discovery of new non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains.
Bioorg Med Chem
; 26(3): 661-674, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29291935
6.
Searching for novel N1-substituted benzimidazol-2-ones as non-nucleoside HIV-1 RT inhibitors.
Bioorg Med Chem
; 25(14): 3861-3870, 2017 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28559060
7.
Structure-guided design of new indoles as negative allosteric modulators (NAMs) of N-methyl-D-aspartate receptor (NMDAR) containing GluN2B subunit.
Bioorg Med Chem
; 24(7): 1513-9, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26912202
8.
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands.
Bioorg Med Chem
; 22(1): 393-7, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24290063
9.
Synthesis, modelling and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-d-aspartate receptors.
Bioorg Med Chem
; 22(3): 1040-8, 2014 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24411196
10.
Targeting GluN2B-containing N-Methyl-D-aspartate receptors: design, synthesis, and binding affinity evaluation of novel 3-substituted indoles.
Arch Pharm (Weinheim)
; 347(8): 533-9, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24862313
11.
Indole derivatives as dual-effective agents for the treatment of neurodegenerative diseases: synthesis, biological evaluation, and molecular modeling studies.
Bioorg Med Chem
; 21(15): 4575-80, 2013 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23777828
12.
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety.
Eur J Med Chem
; 163: 443-452, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30530195
13.
Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases.
Eur J Med Chem
; 143: 276-282, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29197732
14.
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.
Chem Biol Drug Des
; 92(3): 1585-1596, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29729080
15.
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments.
J Med Chem
; 61(9): 3908-3917, 2018 05 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29634898
16.
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors.
Eur J Med Chem
; 125: 992-1001, 2017 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27810600
17.
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides.
J Med Chem
; 60(10): 4316-4326, 2017 05 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-28453941
18.
Rational Design, Synthesis and Evaluation of Coumarin Derivatives as Protein-protein Interaction Inhibitors.
Mol Inform
; 35(8-9): 460-73, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27546050
19.
Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase.
Eur J Med Chem
; 123: 673-683, 2016 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27517812
20.
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms.
Eur J Med Chem
; 102: 223-32, 2015 Sep 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26276436