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1.
Early prediction of decompensation (EPOD) score: Non-invasive determination of cirrhosis decompensation risk.
Liver Int
; 42(3): 640-650, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35007409
2.
Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study.
Thromb J
; 16: 32, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30534008
3.
Modeling and Simulation of In Vivo Drug Effects.
Handb Exp Pharmacol
; 232: 313-29, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26578524
4.
Contribution of rivaroxaban to the international normalized ratio when switching to warfarin for anticoagulation as determined by simulation studies.
Br J Clin Pharmacol
; 79(6): 959-66, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25510952
5.
In-Depth Analysis of the Selection of PBPK Modeling Tools: Bibliometric and Social Network Analysis of the Open Systems Pharmacology Community.
J Clin Pharmacol
; 2024 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38708848
6.
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 79-92, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37794724
7.
Model-informed approach to support pediatric dosing for the pan-PI3K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors.
Clin Transl Sci
; 16(7): 1197-1209, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37042099
8.
Data-driven identification of heart failure disease states and progression pathways using electronic health records.
Sci Rep
; 12(1): 17871, 2022 10 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36284167
9.
Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort.
ERJ Open Res
; 8(4)2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-36329798
10.
CKD subpopulations defined by risk-factors: A longitudinal analysis of electronic health records.
CPT Pharmacometrics Syst Pharmacol
; 10(11): 1343-1356, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34510793
11.
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol
; 10(6): 633-644, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33946131
12.
NT-proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure.
Clin Pharmacol Ther
; 110(2): 498-507, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33630302
13.
Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 782-793, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34053199
14.
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
J Clin Pharmacol
; 61 Suppl 1: S70-S82, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34185905
15.
Algorithmic surveillance of ICU patients with acute respiratory distress syndrome (ASIC): protocol for a multicentre stepped-wedge cluster randomised quality improvement strategy.
BMJ Open
; 11(4): e045589, 2021 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34550901
16.
Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.
Clin Pharmacol Ther
; 109(3): 605-618, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32686076
17.
Multiscale classification of heart failure phenotypes by unsupervised clustering of unstructured electronic medical record data.
Sci Rep
; 10(1): 21340, 2020 12 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33288774
18.
Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
J Clin Pharmacol
; 59 Suppl 1: S95-S103, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31502689
19.
Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban-an oral, direct Factor Xa inhibitor.
Front Physiol
; 5: 417, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25426077
20.
Development of a paediatric population-based model of the pharmacokinetics of rivaroxaban.
Clin Pharmacokinet
; 53(1): 89-102, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23912563