Detalles de la búsqueda
1.
Methyl-tert-butyl ether (MTBE): integration of rat and mouse carcinogenicity data with mode of action and human and rodent bioassay dosimetry and toxicokinetics indicates MTBE is not a plausible human carcinogen.
J Toxicol Environ Health B Crit Rev
; 25(4): 135-161, 2022 05 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35291916
2.
Relevance of mouse lung tumors to human risk assessment.
J Toxicol Environ Health B Crit Rev
; 23(5): 214-241, 2020 07 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32452303
3.
Use of toxicokinetic data for afidopyropen to determine the dose levels in developmental toxicity studies.
Regul Toxicol Pharmacol
; 113: 104644, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32194133
4.
Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop.
Regul Toxicol Pharmacol
; 106: 210-223, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-31059732
5.
Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern.
Regul Toxicol Pharmacol
; 95: 17-28, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29496518
6.
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment.
Regul Toxicol Pharmacol
; 96: 153-166, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29777725
7.
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures.
Toxicol Appl Pharmacol
; 335: 28-40, 2017 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28951217
8.
Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver.
Toxicol Appl Pharmacol
; 332: 149-158, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28392392
9.
IARC use of oxidative stress as key mode of action characteristic for facilitating cancer classification: Glyphosate case example illustrating a lack of robustness in interpretative implementation.
Regul Toxicol Pharmacol
; 86: 157-166, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28274811
10.
How well can carcinogenicity be predicted by high throughput "characteristics of carcinogens" mechanistic data?
Regul Toxicol Pharmacol
; 90: 185-196, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28866267
11.
Human health screening level risk assessments of tertiary-butyl acetate (TBAC): calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations.
Crit Rev Toxicol
; 45(2): 142-71, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25629921
12.
Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4).
Crit Rev Toxicol
; 45(8): 662-726, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25997510
13.
Analysis of Moms Across America report suggesting bioaccumulation of glyphosate in U.S. mother's breast milk: Implausibility based on inconsistency with available body of glyphosate animal toxicokinetic, human biomonitoring, and physico-chemical data.
Regul Toxicol Pharmacol
; 73(3): 758-64, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26520181
14.
Cancer mortality of workers exposed to styrene in the U.S. Reinforced plastics and composite industry.
Epidemiology
; 24(2): 195-203, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23344212
15.
A framework for fit-for-purpose dose response assessment.
Regul Toxicol Pharmacol
; 66(2): 234-40, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23567188
16.
Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing--an integrated approach without additional animal use.
Regul Toxicol Pharmacol
; 63(2): 321-32, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22440553
17.
Use of toxicokinetics to support chemical evaluation: Informing high dose selection and study interpretation.
Regul Toxicol Pharmacol
; 62(2): 241-7, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22198561
18.
A review of the genotoxicity of the industrial chemical cumene.
Mutat Res Rev Mutat Res
; 787: 108364, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34083043
19.
Ethylene Oxide Exposure in U.S. Populations Residing Near Sterilization and Other Industrial Facilities: Context Based on Endogenous and Total Equivalent Concentration Exposures.
Int J Environ Res Public Health
; 18(2)2021 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33445726
20.
Bruce Nathan Ames - Paradigm shifts inside the cancer research revolution.
Mutat Res Rev Mutat Res
; 787: 108363, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34083041