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1.
Bioorthogonal Probes for the Study of MDM2-p53 Inhibitors in Cells and Development of High-Content Screening Assays for Drug Discovery.
Angew Chem Int Ed Engl
; 55(52): 16026-16030, 2016 12 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-27874234
2.
NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo.
Cell Stem Cell
; 31(4): 554-569.e17, 2024 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38579685
3.
A Framework for Optimizing High-Content Imaging of 3D Models for Drug Discovery.
SLAS Discov
; 25(7): 709-722, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32484408
4.
Correction to "2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4".
ACS Med Chem Lett
; 11(11): 2341, 2020 Nov 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33214851
5.
Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing.
J Med Chem
; 63(23): 14576-14593, 2020 12 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33252239
6.
Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4.
J Med Chem
; 63(21): 12542-12573, 2020 11 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32930584
7.
FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer.
Mol Cancer Ther
; 18(12): 2194-2206, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31409633
8.
2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4.
ACS Med Chem Lett
; 9(3): 215-220, 2018 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29541363
9.
Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region.
Medchemcomm
; 8(8): 1604-1613, 2017 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30108871
10.
Studies on oxidopyrylium [5+2] cycloadditions: toward a general synthetic route to the C12-hydroxydaphnetoxins.
Org Lett
; 8(23): 5373-6, 2006 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-17078721
11.
Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors.
J Med Chem
; 58(16): 6348-58, 2015 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26181851
12.
Gateway synthesis of daphnane congeners and their protein kinase C affinities and cell-growth activities.
Nat Chem
; 3(8): 615-9, 2011 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-21778981
13.
Synthesis and Application of a Permanently Immobilized Olefin-Metathesis Catalyst.
Angew Chem Int Ed Engl
; 39(21): 3898-3901, 2000 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29711688
14.
A new approach to (-)-swainsonine by ruthenium-catalyzed ring rearrangement.
J Org Chem
; 67(12): 4325-9, 2002 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-12054970
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