Detalles de la búsqueda
1.
Early Childcare and Education in a Post-Industrial Landscape: Inequalities in Proximity to Active and Relic Manufacturing in Metropolitan Providence, Rhode Island.
Environ Justice
; 16(4): 309-320, 2023 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37614720
2.
Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17ß-hydroxysteroid dehydrogenase (AKR1C3).
Bioorg Med Chem Lett
; 21(5): 1464-8, 2011 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21277203
3.
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies.
Biochem Pharmacol
; 75(2): 484-93, 2008 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17950253
4.
Regulation of progesterone signaling during pregnancy: implications for the use of progestins for the prevention of preterm birth.
J Steroid Biochem Mol Biol
; 139: 173-81, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23410596
5.
Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17ß-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer.
J Med Chem
; 56(6): 2429-46, 2013 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23432095
6.
Development, validation and application of a stable isotope dilution liquid chromatography electrospray ionization/selected reaction monitoring/mass spectrometry (SID-LC/ESI/SRM/MS) method for quantification of keto-androgens in human serum.
J Steroid Biochem Mol Biol
; 138: 281-9, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23851165
7.
Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride.
J Steroid Biochem Mol Biol
; 130(1-2): 7-15, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22265960
8.
Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17ß-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships.
J Med Chem
; 55(5): 2311-23, 2012 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22263837
9.
Role of aldo-keto reductase enzymes in mediating the timing of parturition.
Front Pharmacol
; 2: 92, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22291648
10.
Inhibitors of type 5 17ß-hydroxysteroid dehydrogenase (AKR1C3): overview and structural insights.
J Steroid Biochem Mol Biol
; 125(1-2): 95-104, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21087665
11.
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer.
J Steroid Biochem Mol Biol
; 118(3): 177-87, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20036328
12.
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.
Chem Biol Interact
; 178(1-3): 221-7, 2009 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19010312
13.
Steroid hormone transforming aldo-keto reductases and cancer.
Ann N Y Acad Sci
; 1155: 33-42, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19250190
14.
Formation of 1,4-dioxo-2-butene-derived adducts of 2'-deoxyadenosine and 2'-deoxycytidine in oxidized DNA.
Chem Res Toxicol
; 19(8): 982-5, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16918236
15.
Detection of DNA adducts derived from the reactive metabolite of furan, cis-2-butene-1,4-dial.
Chem Res Toxicol
; 19(3): 414-20, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16544946
16.
The formation of substituted 1,N6-etheno-2'-deoxyadenosine and 1,N2-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan.
Chem Res Toxicol
; 17(12): 1607-13, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15606136
17.
Characterization of nucleoside adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan.
Chem Res Toxicol
; 15(3): 373-9, 2002 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-11896685
Resultados
1 -
17
de 17
1
Próxima >
>>