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1.
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats.
Acta Pharmacol Sin
; 44(3): 499-512, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-36229600
2.
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models.
Acta Pharmacol Sin
; 42(12): 1991-2003, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34531546
3.
Roflumilast, a cyclic nucleotide phosphodiesterase 4 inhibitor, protects against cerebrovascular endothelial injury following cerebral ischemia/reperfusion by activating the Notch1/Hes1 pathway.
Eur J Pharmacol
; 926: 175027, 2022 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35569548
4.
Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway.
Int Immunopharmacol
; 90: 107176, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33243606
5.
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3ß-mediated oxidative stress and IRE1α/TRAF2/JNK pathway.
Free Radic Biol Med
; 163: 281-296, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33359910
6.
Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway.
Redox Biol
; 28: 101342, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31639651
7.
FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3ß/ ß-catenin signaling pathway.
Biochem Pharmacol
; 163: 234-249, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30797872
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