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1.
Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
PLoS Pathog
; 20(6): e1011883, 2024 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38838057
2.
Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates.
Int J Mol Sci
; 24(4)2023 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36834952
3.
Multivalent Tryptophan- and Tyrosine-Containing [60]Fullerene Hexa-Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors.
Chemistry
; 27(41): 10700-10710, 2021 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33851758
4.
Tryptophan Trimers and Tetramers Inhibit Dengue and Zika Virus Replication by Interfering with Viral Attachment Processes.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31932383
5.
(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules
; 24(13)2019 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31247979
6.
Design and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2H-Benzo[g]indazole Derivatives: Antiproliferative and Antibacterial Activity.
Molecules
; 24(23)2019 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31766444
7.
A Novel Class of Cationic and Non-Peptidic Small Molecules as Hits for the Development of Antimicrobial Agents.
Molecules
; 23(7)2018 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29932141
8.
Optimization of a Class of Tryptophan Dendrimers That Inhibit HIV Replication Leads to a Selective, Specific, and Low-Nanomolar Inhibitor of Clinical Isolates of Enterovirus A71.
Antimicrob Agents Chemother
; 60(8): 5064-7, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27246775
9.
Multivalent agents containing 1-substituted 2,3,4-trihydroxyphenyl moieties as novel synthetic polyphenols directed against HIV-1.
Org Biomol Chem
; 12(28): 5278-94, 2014 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24927059
10.
Probing the dimerization interface of Leishmania infantum trypanothione reductase with site-directed mutagenesis and short peptides.
Chembiochem
; 14(10): 1212-7, 2013 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-23744811
11.
Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors.
Eur J Med Chem
; 237: 114414, 2022 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35512567
12.
Interrogation of Essentiality in the Reconstructed Haemophilus influenzae Metabolic Network Identifies Lipid Metabolism Antimicrobial Targets: Preclinical Evaluation of a FabH ß-Ketoacyl-ACP Synthase Inhibitor.
mSystems
; 7(2): e0145921, 2022 04 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35293791
13.
A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro.
Pharmaceuticals (Basel)
; 15(8)2022 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36015168
14.
Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library.
Eur J Med Chem
; 243: 114675, 2022 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36075146
15.
Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity.
Eur J Med Chem
; 244: 114878, 2022 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36332553
16.
HIV-1 Envelope Spike MPER: From a Vaccine Target to a New Druggable Pocket for Novel and Effective Fusion Inhibitors.
ChemMedChem
; 16(1): 105-107, 2021 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33428329
17.
Inhibition of XPO-1 Mediated Nuclear Export through the Michael-Acceptor Character of Chalcones.
Pharmaceuticals (Basel)
; 14(11)2021 Nov 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34832913
18.
Small Molecule-Peptide Conjugates as Dimerization Inhibitors of Leishmania infantum Trypanothione Disulfide Reductase.
Pharmaceuticals (Basel)
; 14(7)2021 Jul 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-34358115
19.
Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles.
J Med Chem
; 64(9): 6137-6160, 2021 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33945281
20.
Double Arylation of the Indole Side Chain of Tri- and Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors.
J Med Chem
; 64(14): 10027-10046, 2021 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34229438