Detalles de la búsqueda
1.
Efficacy of Delafloxacin versus Moxifloxacin against Bacterial Respiratory Pathogens in Adults with Community-Acquired Bacterial Pneumonia (CABP): Microbiology Results from the Delafloxacin Phase 3 CABP Trial.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31844013
2.
Evidence-Based Study Design for Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia.
J Infect Dis
; 219(10): 1536-1544, 2019 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30649434
3.
Analysis of Pooled Phase III Efficacy Data for Delafloxacin in Acute Bacterial Skin and Skin Structure Infections.
Clin Infect Dis
; 68(Suppl 3): S223-S232, 2019 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30957167
4.
Efficacy and Safety of Single-Dose Oral Delafloxacin Compared With Intramuscular Ceftriaxone for Uncomplicated Gonorrhea Treatment: An Open-Label, Noninferiority, Phase 3, Multicenter, Randomized Study.
Sex Transm Dis
; 46(5): 279-286, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30985632
5.
A Comparison of the Efficacy and Safety of Intravenous Followed by Oral Delafloxacin With Vancomycin Plus Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections: A Phase 3, Multinational, Double-Blind, Randomized Study.
Clin Infect Dis
; 67(5): 657-666, 2018 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29518178
6.
A randomized, double-blind, Phase 2 study to evaluate subjective and objective outcomes in patients with acute bacterial skin and skin structure infections treated with delafloxacin, linezolid or vancomycin.
J Antimicrob Chemother
; 71(3): 821-9, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26679243
7.
A thorough QT study to evaluate the effects of therapeutic and supratherapeutic doses of delafloxacin on cardiac repolarization.
Antimicrob Agents Chemother
; 59(6): 3469-73, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25845864
8.
Efficacy of delafloxacin versus moxifloxacin against atypical bacterial respiratory pathogens in adults with community-acquired bacterial pneumonia (CABP): Data from the Delafloxacin Phase 3 CABP Trial.
Int J Infect Dis
; 97: 374-379, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32534142
9.
A Phase 3 Study to Compare Delafloxacin With Moxifloxacin for the Treatment of Adults With Community-Acquired Bacterial Pneumonia (DEFINE-CABP).
Open Forum Infect Dis
; 7(1): ofz514, 2020 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-31988972
10.
Safety of Delafloxacin: Focus on Adverse Events of Special Interest.
Open Forum Infect Dis
; 5(10): ofy220, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30349845
11.
Delafloxacin Pharmacokinetics in Subjects With Varying Degrees of Renal Function.
J Clin Pharmacol
; 58(4): 514-521, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29251785
12.
Clinical Pharmacokinetics of Sulfobutylether-ß-Cyclodextrin in Patients With Varying Degrees of Renal Impairment.
J Clin Pharmacol
; 58(6): 814-822, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29578585
13.
Pharmacokinetics of Intravenous Delafloxacin in Patients With End-Stage Renal Disease.
J Clin Pharmacol
; 58(7): 913-919, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29537614
14.
The Pharmacokinetics of the CYP3A Substrate Midazolam After Steady-state Dosing of Delafloxacin.
Clin Ther
; 39(6): 1182-1190, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28495029
15.
Clinical Pharmacology of Delafloxacin in Patients With Hepatic Impairment.
J Clin Pharmacol
; 57(3): 328-335, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27570245
16.
Single and Multiple Ascending-dose Studies of Oral Delafloxacin: Effects of Food, Sex, and Age.
Clin Ther
; 38(1): 39-52, 2016 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26581327
17.
Safety, Tolerability, and Pharmacokinetic Properties of Intravenous Delafloxacin After Single and Multiple Doses in Healthy Volunteers.
Clin Ther
; 38(1): 53-65, 2016 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26718605
18.
A randomized phase 2 study comparing two doses of delafloxacin with tigecycline in adults with complicated skin and skin-structure infections.
Int J Infect Dis
; 30: 67-73, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25448332
19.
Linezolid does not increase the risk of thrombocytopenia in patients with nosocomial pneumonia: comparative analysis of linezolid and vancomycin use.
Clin Infect Dis
; 37(12): 1609-16, 2003 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14689341
20.
Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.
Chest
; 124(5): 1789-97, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14605050