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1.
Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on ß-Amyloid Aggregation and Neurotoxicity.
Molecules
; 23(7)2018 06 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29949947
2.
Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on ß-amyloid(1-40) aggregation and toxicity.
Arch Biochem Biophys
; 560: 73-82, 2014 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25051344
3.
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Abeta1-40 aggregation in vitro.
Bioorg Med Chem
; 16(9): 4810-22, 2008 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18406152
4.
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
Bioorg Med Chem
; 16(22): 9780-9, 2008 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18938084
5.
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives.
J Med Chem
; 50(22): 5364-71, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17910428
6.
Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity.
Eur J Pharm Sci
; 109: 381-388, 2017 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28801274
7.
Synthesis, central and peripheral benzodiazepine receptor affinity of pyrazole and pyrazole-containing polycyclic derivatives.
Farmaco
; 59(11): 849-56, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15544788
8.
Synthesis and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors.
Farmaco
; 58(2): 129-40, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12581779
9.
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2.
Farmaco
; 57(1): 63-9, 2002 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-11902647
10.
Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
Eur J Med Chem
; 58: 84-97, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23108363
11.
ß-D-glucosyl conjugates of highly potent inhibitors of blood coagulation factor Xa bearing 2-chorothiophene as a P1 motif.
ChemMedChem
; 7(9): 1669-77, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22851501
12.
Synthesis and biophysical evaluation of arylhydrazono-1H-2-indolinones as ß-amyloid aggregation inhibitors.
Eur J Med Chem
; 46(1): 275-84, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21144622
13.
Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as beta-amyloid aggregation inhibitors.
Eur J Med Chem
; 45(4): 1359-66, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20137834
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