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1.
In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species.
J Antimicrob Chemother
; 67(2): 387-97, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22127582
2.
In vitro Leishmanicidal and Trypanosomicidal Properties of Imidazole-Containing Azine and Benzoazine Derivatives.
ChemMedChem
; 16(23): 3600-3614, 2021 12 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34665510
3.
Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.
Bioorg Med Chem
; 18(14): 5301-9, 2010 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20538470
4.
Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings.
J Med Chem
; 51(6): 1962-6, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18293910
5.
Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative.
Eur J Med Chem
; 106: 106-19, 2015 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26523668
6.
A Proton-Ionizable Ester Crown of 3,5-Disubstituted 1H-Pyrazole Able To Form Stable Dinuclear Complexes with Lipophilic Phenethylamines.
J Org Chem
; 62(9): 2684-2693, 1997 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-11671626
7.
Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection.
J Med Chem
; 55(22): 9900-13, 2012 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23043291
8.
In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.
J Med Chem
; 54(4): 970-9, 2011 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-21229977
9.
1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi.
Bioorg Med Chem
; 15(5): 2081-91, 2007 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17222558
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