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1.
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers.
Acta Pharmacol Sin
; 43(10): 2678-2686, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35228653
2.
Gene Cloning and Expression of Cellulase of Bacillus amyloliquefaciens Isolated from the Cecum of Goose.
Anim Biotechnol
; 28(1): 74-82, 2017 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27575333
3.
Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment.
Eur J Pharmacol
; 952: 175752, 2023 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37164118
4.
Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus.
Signal Transduct Target Ther
; 8(1): 143, 2023 04 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37015918
5.
Nintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours.
Mol Oncol
; 16(8): 1761-1774, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35194937
6.
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML).
Eur J Pharmacol
; 897: 173944, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33581133
7.
Discovery of (S)-2-(1-(4-Amino-3-(3-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)propyl)-3-cyclopropyl-5-fluoroquinazolin-4(3H)-one (IHMT-PI3Kδ-372) as a Potent and Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease.
J Med Chem
; 63(22): 13973-13993, 2020 11 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33180507
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