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1.
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation.
ChemMedChem
; 15(7): 643-658, 2020 04 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32003940
2.
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.
ACS Med Chem Lett
; 11(5): 754-759, 2020 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32435381
3.
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
Bioorg Med Chem
; 16(15): 7450-6, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18585045
4.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
Future Med Chem
; 9(11): 1161-1174, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28722470
5.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J Med Chem
; 60(5): 1693-1715, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186757
6.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
J Med Chem
; 60(5): 1673-1692, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186755
7.
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.
J Med Chem
; 59(4): 1501-17, 2016 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26702542
8.
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Eur J Med Chem
; 86: 352-63, 2014 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-25173853
9.
Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo.
J Med Chem
; 57(12): 5333-47, 2014 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-24918261
10.
Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors.
J Med Chem
; 53(2): 822-39, 2010 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20017493
11.
A Simple Method for the Selective Deprotection of p-Methoxybenzyl Ethers by Cerium(III) Chloride Heptahydrate and Sodium Iodide.
J Org Chem
; 64(15): 5696-5699, 1999 Jul 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-11674643
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