Detalles de la búsqueda
1.
Synthesis of novel 4-Boc-piperidone chalcones and evaluation of their cytotoxic activity against highly-metastatic cancer cells.
Bioorg Med Chem Lett
; 30(1): 126760, 2020 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31767266
2.
Screening Marine Natural Products for New Drug Leads against Trypanosomatids and Malaria.
Mar Drugs
; 18(4)2020 Mar 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-32244488
3.
Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation.
J Biol Chem
; 293(43): 16923-16930, 2018 10 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30201608
4.
Biological and structural effects of the conjugation of an antimicrobial decapeptide with saturated, unsaturated, methoxylated and branched fatty acids.
J Pept Sci
; 23(1): 45-55, 2017 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28025839
5.
Chemical conjugation of 2-hexadecynoic acid to C5-curcumin enhances its antibacterial activity against multi-drug resistant bacteria.
Bioorg Med Chem Lett
; 25(22): 5067-71, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26483137
6.
Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity.
Bioorg Med Chem Lett
; 25(10): 2174-80, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25881826
7.
2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes.
Bioorg Med Chem Lett
; 24(17): 4151-7, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25103602
8.
Synthesis of marine α-methoxylated fatty acid analogs that effectively inhibit the topoisomerase IB from Leishmania donovani with a mechanism different from that of camptothecin.
Mar Drugs
; 11(10): 3661-75, 2013 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-24084785
9.
First total synthesis of the (±)-2-methoxy-6-heptadecynoic acid and related 2-methoxylated analogs as effective inhibitors of the leishmania topoisomerase IB enzyme.
Pure Appl Chem
; 84(9): 1867-1875, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23118491
10.
2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.
Bioorg Med Chem Lett
; 22(19): 6185-9, 2012 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22932312
11.
Vinyl halogenated fatty acids display antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus.
Med Res Arch
; 10(7)2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-36118101
12.
Antiprotozoal activity of Melampyrum arvense and its metabolites.
Phytother Res
; 25(1): 142-6, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20623589
13.
Antibacterial fatty acids: An update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents.
Prog Lipid Res
; 82: 101093, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33577909
14.
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.
Bioorg Med Chem
; 18(21): 7475-85, 2010 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20855214
15.
The first total synthesis of the (±)-17-methyl-trans-4,5-methyleneoctadecanoic acid and related analogs with antileishmanial activity.
Tetrahedron Lett
; 51(47): 6153-6155, 2010 Nov 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-21218160
16.
Antibacterial Activity of Hexadecynoic Acid Isomers toward Clinical Isolates of Multidrug-Resistant Staphylococcus aureus.
Lipids
; 55(2): 101-116, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31975430
17.
The first total synthesis of (±)-4-methoxydecanoic acid: a novel antifungal fatty acid.
Tetrahedron Lett
; 50(41): 5699-5700, 2009 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20161109
18.
First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties.
Curr Top Med Chem
; 18(5): 418-427, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29766807
19.
Synthesis and antifungal properties of alpha-methoxy and alpha-hydroxyl substituted 4-thiatetradecanoic acids.
Chem Phys Lipids
; 150(1): 82-8, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17662704
20.
First total syntheses of (Z)-15-methyl-10-hexadecenoic acid and the (Z)-13-methyl-8-tetradecenoic acid.
Chem Phys Lipids
; 145(1): 37-44, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17125759