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1.
Nanobody inhibitors of Plexin-B1 identify allostery in plexin-semaphorin interactions and signaling.
J Biol Chem
; 299(6): 104740, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37088134
2.
Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80.
J Biol Chem
; 299(1): 102769, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36470427
3.
Discovery of a novel pseudo ß-hairpin structure of N-truncated amyloid-ß for use as a vaccine against Alzheimer's disease.
Mol Psychiatry
; 27(2): 840-848, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34776512
4.
Allosteric activation of MALT1 by its ubiquitin-binding Ig3 domain.
Proc Natl Acad Sci U S A
; 117(6): 3093-3102, 2020 02 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31980531
5.
Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc Natl Acad Sci U S A
; 117(29): 16949-16960, 2020 07 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32616569
6.
Conformational dynamics in interleukin 17A and 17F functional complexes is a key determinant of receptor A affinity and specificity.
Cytokine
; 142: 155476, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33706174
7.
Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol
; 16(5): e2006192, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29782488
8.
Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.
J Biol Chem
; 293(31): 12149-12166, 2018 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29925589
9.
Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES.
J Biol Chem
; 291(32): 16840-8, 2016 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27231345
10.
Conformational heterogeneity in antibody-protein antigen recognition: implications for high affinity protein complex formation.
J Biol Chem
; 289(10): 7200-7210, 2014 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24436329
11.
Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.
J Biol Chem
; 288(20): 14438-14450, 2013 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23548911
12.
Structure and interactions of the human programmed cell death 1 receptor.
J Biol Chem
; 288(17): 11771-85, 2013 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23417675
13.
Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
J Biol Chem
; 287(47): 40043-50, 2012 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23027872
14.
Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.
J Biol Chem
; 287(32): 26464-77, 2012 Aug 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-22696217
15.
Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery.
Front Immunol
; 14: 1216967, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37483614
16.
Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism.
Chem Sci
; 14(27): 7524-7536, 2023 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37449080
17.
Solution structure of the Mycobacterium tuberculosis EsxG·EsxH complex: functional implications and comparisons with other M. tuberculosis Esx family complexes.
J Biol Chem
; 286(34): 29993-30002, 2011 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21730061
18.
Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor.
J Biol Chem
; 286(19): 17270-80, 2011 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21454508
19.
The statistical significance of selected sense-antisense peptide interactions.
J Comput Chem
; 33(16): 1440-7, 2012 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22488506
20.
Sequence-specific 1H, 13C and 15N backbone NMR assignments for the N-terminal IgV-like domain (D1) and full extracellular region (D1D2) of PD-L1.
Biomol NMR Assign
; 16(2): 281-288, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35675028