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1.
Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity.
J Pharmacol Exp Ther
; 333(3): 707-16, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20228155
2.
Part II: piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.
Bioorg Med Chem Lett
; 20(4): 1388-94, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20097563
3.
Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.
Bioorg Med Chem Lett
; 19(16): 4657-63, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19604694
4.
Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation.
Bioorg Med Chem Lett
; 19(21): 6148-56, 2009 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19796941
5.
Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.
J Med Chem
; 46(19): 4050-62, 2003 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12954058
6.
Administration of a small molecule tissue factor/factor VIIa inhibitor in a non-human primate thrombosis model of venous thrombosis: effects on thrombus formation and bleeding time.
Thromb Res
; 112(3): 167-74, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14967414
7.
A method for determining whether hypotension caused by novel compounds in preclinical development results from histamine release.
J Pharmacol Toxicol Methods
; 49(1): 31-7, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-14670692
8.
Discovery of novel cyanodihydropyridines as potent mineralocorticoid receptor antagonists.
J Med Chem
; 53(16): 5970-8, 2010 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-20672820
9.
Piperazinyl glutamate pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.
J Med Chem
; 53(5): 2010-37, 2010 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-20141147
10.
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS).
ACS Med Chem Lett
; 1(2): 59-63, 2010 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900177
11.
Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.
Bioorg Med Chem Lett
; 13(14): 2319-25, 2003 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-12824026
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