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1.
Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.
Drug Metab Dispos
; 52(3): 153-158, 2024 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38216306
2.
Disposition of [14C]LY2606368 following intravenous administration in patients with advanced and/or metastatic solid tumours.
Xenobiotica
; 50(7): 793-804, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-31847673
3.
Qualitative and quantitative prediction of human in vivo metabolic pathways in a human hepatocyte-murine stromal cell co-culture model.
Xenobiotica
; 48(12): 1192-1205, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29143555
4.
Disposition and metabolism of [14C]-galunisertib, a TGF-ßRI kinase/ALK5 inhibitor, following oral administration in healthy subjects and mechanistic prediction of the effect of itraconazole on galunisertib pharmacokinetics.
Xenobiotica
; 48(4): 382-399, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28436712
5.
Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats.
Drug Metab Dispos
; 44(8): 1184-92, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27217490
6.
Disposition and metabolism of LY2603618, a Chk-1 inhibitor following intravenous administration in patients with advanced and/or metastatic solid tumors.
Xenobiotica
; 44(9): 827-41, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24666335
7.
Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.
Clin Pharmacol Ther
; 115(5): 931-938, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38018358
8.
Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure.
Drug Metab Dispos
; 41(4): 714-26, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23305709
9.
Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.
Clin Pharmacol Ther
; 113(4): 775-781, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35733280
10.
Enterohepatic circulation of glucuronide metabolites of drugs in dog.
Pharmacol Res Perspect
; 7(4): e00502, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31333846
11.
Identification and Mitigation of Reactive Metabolites of 2-Aminoimidazole-Containing Microsomal Prostaglandin E Synthase-1 Inhibitors Terminated Due to Clinical Drug-Induced Liver Injury.
J Med Chem
; 61(5): 2041-2051, 2018 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29425457
12.
Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm.
ACS Med Chem Lett
; 5(10): 1138-42, 2014 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25313327
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