Detalles de la búsqueda
1.
2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives.
Molecules
; 29(11)2024 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38893418
2.
Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation.
J Enzyme Inhib Med Chem
; 38(1): 2209828, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37184096
3.
Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons.
Int J Mol Sci
; 24(18)2023 Sep 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37762529
4.
Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia.
Molecules
; 28(10)2023 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37241951
5.
In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1.
Neurochem Res
; 47(6): 1778-1789, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35380398
6.
Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties.
Molecules
; 27(4)2022 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35209087
7.
1-(2'-Bromobenzyl)-6,7-dihydroxy-N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D2 Dopamine Receptors.
J Nat Prod
; 83(1): 127-133, 2020 01 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31933369
8.
2-Aryladenine derivatives as a potent scaffold for A1, A3 and dual A1/A3 adenosine receptor antagonists: Synthesis and structure-activity relationships.
Bioorg Med Chem
; 27(16): 3551-3558, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31280999
9.
New Nitrogen Compounds Coupled to Phenolic Units with Antioxidant and Antifungal Activities: Synthesis and Structureâ»Activity Relationship.
Molecules
; 23(10)2018 Oct 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30282927
10.
Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D2 Receptor Ligand.
Molecules
; 23(9)2018 Sep 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30181442
11.
G Protein-Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches.
Mol Pharmacol
; 88(3): 561-71, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26138074
12.
Computer-aided structure-based design of multitarget leads for Alzheimer's disease.
J Chem Inf Model
; 55(1): 135-48, 2015 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25483751
13.
Discovery and inâ vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening.
ChemMedChem
; : e202400080, 2024 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38619283
14.
A subchronic history of binge-drinking elicits mild, age- and sex-selective, affective, and cognitive anomalies in C57BL/6J mice.
Front Behav Neurosci
; 17: 1192076, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37600758
15.
Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents - Design, synthesis, structural studies and pharmacological profiling.
Eur J Med Chem
; 252: 115285, 2023 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37027998
16.
Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications.
Pharmacol Rep
; 74(2): 406-424, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35064921
17.
Multitarget Derivatives of D2AAK1 as Potential Antipsychotics: The Effect of Substitution in the Indole Moiety.
ChemMedChem
; 17(15): e202200238, 2022 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35610178
18.
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.
Nat Chem Biol
; 5(10): 734-42, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19701185
19.
Synthesis of novel chromene scaffolds for adenosine receptors.
Org Biomol Chem
; 9(11): 4242-9, 2011 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21509353
20.
Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of ß-arrestin-2 and activate Gα13.
Biochem J
; 432(3): 451-9, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20919992