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1.
C-terminal modification of a de novo designed antimicrobial peptide via capping of macrolactam rings.
Bioorg Chem
; 130: 106251, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36370649
2.
Bioisosteric investigation of ebselen: Synthesis and in vitro characterization of 1,2-benzisothiazol-3(2H)-one derivatives as potent New Delhi metallo-ß-lactamase inhibitors.
Bioorg Chem
; 100: 103873, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32361294
3.
Hydrophobic substituents on isatin derivatives enhance their inhibition against bacterial peptidoglycan glycosyltransferase activity.
Bioorg Chem
; 97: 103710, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32146179
4.
Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C ß-Lactamases.
Antimicrob Agents Chemother
; 61(12)2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28971874
5.
A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo.
Mol Pharm
; 12(10): 3507-17, 2015 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26291333
6.
In vitro and in vivo efficacy of novel flavonoid dimers against cutaneous leishmaniasis.
Antimicrob Agents Chemother
; 58(6): 3379-88, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24687505
7.
A novel ESKAPE-sensitive peptide with enhanced stability and its application in controlling multiple bacterial contaminations in chilled fresh pork.
Food Chem
; 413: 135647, 2023 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36796263
8.
Identification of isothiazolones analogues as potent bactericidal agents against antibiotic resistant CRE and MRSA strains.
BMC Chem
; 17(1): 183, 2023 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38104171
9.
An ornithine-rich dodecapeptide with improved proteolytic stability selectively kills gram-negative food-borne pathogens and its action mode on Escherichia coli O157:H7.
Int J Food Microbiol
; 352: 109281, 2021 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-34126526
10.
Investigation of antibiofilm activity, antibacterial activity, and mechanistic studies of an amphiphilic peptide against Acinetobacter baumannii.
Biochim Biophys Acta Biomembr
; 1863(6): 183600, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33675719
11.
Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2).
J Med Chem
; 64(19): 14311-14331, 2021 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34606270
12.
De Novo Designed Hexadecapeptides Synergize Glycopeptide Antibiotics Vancomycin and Teicoplanin against Pathogenic Klebsiella pneumoniae via Disruption of Cell Permeability and Potential.
ACS Appl Bio Mater
; 3(3): 1738-1752, 2020 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35021663
13.
Quinacrine and a novel apigenin dimer can synergistically increase the pentamidine susceptibility of the protozoan parasite Leishmania.
J Antimicrob Chemother
; 63(6): 1179-90, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19377065
14.
Phenol-Soluble-Modulin-Inspired Amphipathic Peptides Have Bactericidal Activity against Multidrug-Resistant Bacteria.
ChemMedChem
; 14(16): 1547-1559, 2019 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31359624
15.
Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
J Med Chem
; 62(18): 8578-8608, 2019 09 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31465686
16.
Antibacterial activity and mechanism of action of a thiophenyl substituted pyrimidine derivative.
RSC Adv
; 9(19): 10739-10744, 2019 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35515309
17.
Design, synthesis and antibacterial evaluation of 2,4-disubstituted-6-thiophenyl-pyrimidines.
Eur J Med Chem
; 161: 141-153, 2019 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30347327
18.
Boosting the efficacy of anti-MRSA ß-lactam antibiotics via an easily accessible, non-cytotoxic and orally bioavailable FtsZ inhibitor.
Eur J Med Chem
; 163: 95-115, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30503946
19.
Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry".
J Med Chem
; 61(22): 9931-9951, 2018 11 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-30351934
20.
Investigation of synergistic antimicrobial effects of the drug combinations of meropenem and 1,2-benzisoselenazol-3(2H)-one derivatives on carbapenem-resistant Enterobacteriaceae producing NDM-1.
Eur J Med Chem
; 155: 285-302, 2018 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29894943