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1.
Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus.
Bioorg Med Chem Lett
; 21(10): 2925-9, 2011 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21486696
2.
Structure-activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties.
Bioorg Med Chem Lett
; 18(9): 2845-9, 2008 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18424044
3.
Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases.
J Med Chem
; 47(24): 5894-911, 2004 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-15537345
4.
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3(1,2).
J Med Chem
; 45(24): 5233-48, 2002 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-12431051
5.
Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase.
J Med Chem
; 57(5): 1855-79, 2014 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24397558
6.
Methylsulfonylpyrazolyl oxadiazoles and thiadiazoles as potent, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
Future Med Chem
; 1(5): 947-67, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21426091
7.
The tertiary structure and domain organization of coagulation factor VIII.
Blood
; 111(3): 1240-7, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17965321
8.
Biarylpyrazolyl oxadiazole as potent, selective, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
J Med Chem
; 51(22): 7216-33, 2008 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18954042
9.
SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa.
Bioorg Med Chem Lett
; 17(16): 4419-27, 2007 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17588746
10.
Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors.
J Comput Aided Mol Des
; 19(2): 111-22, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16075305
11.
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3.
Bioorg Med Chem Lett
; 14(2): 343-6, 2004 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-14698155
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