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1.
Design of a structure-activity relationship model of vitamin K epoxide reductase (VKORC1) inhibitors combining chemical synthesis of new compounds, enzymatic assays and molecular modelling.
Bioorg Med Chem
; 94: 117453, 2023 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37741121
2.
Structural Investigation of the Vitamin K Epoxide Reductase (VKORC1) Binding Site with Vitamin K.
Biochemistry
; 59(13): 1351-1360, 2020 04 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32182040
3.
Comparative biological properties of the four stereoisomers of difethialone, a second-generation anticoagulant rodenticide, in rats: development of a model allowing to choose the appropriate stereoisomeric ratio.
Arch Toxicol
; 94(3): 795-801, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32047980
4.
Structural investigation of vitamin K epoxide reductase domain-containing protein in Leptospira species: a potential target for the development of new leptospirosis treatments as an alternative to antibiotics.
J Biomol Struct Dyn
; : 1-13, 2024 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38197604
5.
Exposure and resistance to anticoagulant rodenticides in invasive and endemic Chadian urban rodent species to develop a rational management strategy.
Pest Manag Sci
; 2023 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38031300
6.
Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1.
Nutrients
; 11(1)2019 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30609653
7.
Elevated difenacoum metabolism is involved in the difenacoum-resistant phenotype observed in Berkshire rats homozygous for the L120Q mutation in the vitamin K epoxide reductase complex subunit 1 (Vkorc1) gene.
Pest Manag Sci
; 74(6): 1328-1334, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29155484
8.
Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus: identification and characterisation of a novel Y25F mutation in the Vkorc1 gene.
Pest Manag Sci
; 72(3): 544-50, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25847836
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