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1.
Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.
Biochemistry
; 48(23): 5339-49, 2009 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19459657
2.
Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor.
J Med Chem
; 52(5): 1255-8, 2009 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-19209845
3.
In vitro resistance study of AG-021541, a novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Antimicrob Agents Chemother
; 52(2): 675-83, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18070954
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