Detalles de la búsqueda
1.
FK506-binding protein 2 (FKBP13) inhibit Bax-induced apoptosis in Saccharomyces cerevisiae (yeast).
Cell Biol Toxicol
; 39(3): 719-728, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34342774
2.
Identification of proteins involved in transcription/translation (eEF 1A1) as an inhibitor of Bax induced apoptosis.
Mol Biol Rep
; 47(9): 6785-6792, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32875432
3.
Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink.
Sensors (Basel)
; 20(14)2020 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32708163
4.
Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast.
Bioorg Med Chem Lett
; 29(3): 454-460, 2019 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30579794
5.
Radicicol rescues yeast cell death triggered by expression of human α-synuclein and its A53T mutant, but not by human ßA4 peptide and proapoptotic protein bax.
Bioorg Chem
; 85: 152-158, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30612081
6.
Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells.
Bioorg Med Chem
; 26(23-24): 6076-6086, 2018 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30448188
7.
Glycyrrhiza glabra extract and quercetin reverses cisplatin resistance in triple-negative MDA-MB-468 breast cancer cells via inhibition of cytochrome P450 1B1 enzyme.
Bioorg Med Chem Lett
; 27(24): 5400-5403, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29150398
8.
Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance.
Bioorg Med Chem Lett
; 27(16): 3683-3687, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28711350
9.
(E)-3-(3,4,5-Trimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one, a heterocyclic chalcone is a potent and selective CYP1A1 inhibitor and cancer chemopreventive agent.
Bioorg Med Chem Lett
; 27(24): 5409-5414, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29138024
10.
Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human Cells.
J Chem Inf Model
; 57(6): 1309-1320, 2017 06 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-28489395
11.
Biphenyl urea derivatives as selective CYP1B1 inhibitors.
Org Biomol Chem
; 14(38): 8931-8936, 2016 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-27714268
12.
Corrigendum to "Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast" [Bioorg. Med. Chem. Lett. 29 (2019) 454-460].
Bioorg Med Chem Lett
; 29(16): 2437-2438, 2019 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31281017
13.
Human VAMP3 Suppresses or Negatively Regulates Bax Induced Apoptosis in Yeast.
Biomedicines
; 9(1)2021 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33478086
14.
Apoptosis, Induced by Human α-Synuclein in Yeast, Can Occur Independent of Functional Mitochondria.
Cells
; 9(10)2020 09 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-33003464
15.
The effect of copy number on α-synuclein's toxicity and its protective role in Bax-induced apoptosis, in yeast.
Biosci Rep
; 40(9)2020 09 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-32794578
16.
Conversion of amino acids to aryl/heteroaryl ethanol metabolites using human CYP2D6-expressing live baker's yeast.
RSC Med Chem
; 11(1): 142-147, 2020 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33479614
17.
Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1.
Bioorg Med Chem
; 17(16): 6073-84, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19632122
18.
Inhibitors of Aß42-induced endoplasmic reticular unfolded protein response (UPRER), in yeast, also rescue yeast cells from Aß42-mediated apoptosis.
Eur J Pharm Sci
; 128: 118-127, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30502452
19.
Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.
Eur J Med Chem
; 165: 115-132, 2019 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30665142
20.
CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance.
Eur J Pharm Sci
; 131: 177-194, 2019 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30776468